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Edukacja w zakresie insulinoterapii i samokontroli pacjentów z cukrzycą w podstawowej opiece zdrowotnej – doniesienie wstępne

100%
Mizik-Łukowska M., Gacka M., Adamiec R.
Pediatria i Medycyna Rodzinna
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2015
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vol. 11
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issue 2
177-185
EN
The aim of this paper was to assess the compliance with the basic principles of insulin self-administration and the selfmonitoring of blood glucose levels. Materials and methods: The study was conducted using author’s anonymous questionnaire to be completed by patients receiving insulin therapy. The questionnaires were completed by 73 patients (72% with type 2 diabetes, 18% with type 1 diabetes) who visited their family physician during the period of 3 months in 2013. Results: A total of 22 patients did not comply with the recommended interval between the administration of premeal insulin and a meal, 24 patients never measured their blood glucose levels after a meal, and as many as 57 respondents did not practice periodic self-measurements of night-time blood glucose levels. Most patients (42 respondents) reported the hospital as a place of insulin therapy training, whereas regional outpatient clinics (physicians and nurses) came second. Only 6 respondents reported diabetes clinics as the place of training. Also, 6 respondents stored their currently used insulin in a refrigerator. Conclusions: Patients receiving insulin therapy require a continuous re-education as well as periodic verification of the basic principles for the use of insulin therapy and the self-monitoring of blood glucose levels.
PL
Celem pracy była ocena przestrzegania podstawowych zasad podawania insuliny i samokontroli glikemii u pacjentów z cukrzycą. Materiał i metody: Badanie przeprowadzono za pomocą autorskiej anonimowej ankiety wypełnianej przez pacjentów stosujących insulinoterapię. Ankietę wypełniły 73 osoby (72% z cukrzycą typu 2, 18% z cukrzycą typu 1), które zgłosiły się do lekarza rodzinnego w ciągu 3 miesięcy w 2013 roku. Wyniki: Zaleconego przedziału czasowego pomiędzy podaniem insuliny doposiłkowej a posiłkiem nie przestrzegało 22 pacjentów, 24 nigdy nie oznaczało glikemii po posiłku, a aż 57 nie prowadziło okresowych pomiarów glikemii nocnych. Najwięcej chorych podawało szpital jako miejsce szkolenia z zakresu insulinoterapii (42 osoby), w drugiej kolejności wymieniano przychodnię rejonową (lekarz i pielęgniarki). Tylko 6 osób wskazało jako miejsce szkolenia poradnie diabetologiczne. Również 6 osób przechowywało aktualnie stosowaną insulinę w lodówce. Wnioski: Pacjenci przyjmujący insulinę wymagają ciągłej reedukacji i okresowej weryfikacji podstawowych zasad stosowania insulinoterapii i samokontroli glikemii.
2
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Is the 65 kDa protein a direct signal for the nuclease release from nuclear matrix, the apoptotic cascade?

87%
Szopa J., Adamiec R.
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3
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A relationship between serological markers of chronic C. pneumoniae and CMV infection and hsp60 in patients with atherosclerotic carotid stenosis

76%
Rabczyński M., Fiodorenko-Dumas Ż., Mastej K., Dumas I., Adamiec R., Paprocka-Borowicz M.
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2015
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vol. 62
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issue 1
89-95
EN
A number of epidemiological studies conducted over the last decade indicate a relationship between specific pathogen infections and the development of atherosclerosis, although no pathogenetic pathways connecting these two have been determined. Recent reports support the role of heat shock proteins (HSPs) in atherogenesis. The HSPs are also believed to be a link between the infection and the development of atherosclerotic lesions. The aims of study: Immunohistochemical evaluation of carotid artery segments to show the relationship between the presence of heat shock proteins and the serum levels of anti-hsp60 antibodies. An attempt to demonstrate a relationship between an expression of chronic C. pneumoniae and CMV antigens. Material and Methods: The study included 41 patients qualified for carotid artery endarterectomy and 18 healthy volunteers of corresponding age. Levels of anti- hsp60, anti-C. pneumoniae IgA and IgG, anti-CMV IgG antibodies as well as hsCRP were determined. Results: The mean serum levels of anti-hsp60 antibodies were higher in patients with advanced atherosclerosis as compared to healthy volunteers (55.3±64.1 vs 32.8±29.8; p < 0.05). There was a strong correlation between anti-hsp60 antibodies and the expression of hsp60 in carotid arterial wall, as confirmed by immunohistochemical evaluation. The study group showed statistically significant higher levels of hsCRP. Furthermore, statistically significant higher serum levels of anti-C. pneumoniae IgG and IgA as well as anti-CMV IgG antibodies were found in the study group as compared to controls. No correlation was shown between the markers of chronic infection induced by the tested pathogens and serum levels of anti-HSP and hsCRP. Conclusions: Higher protein expression in vascular walls is closely correlated with the level of anti-hsp60. At the same time, no significant relationship between anti-hsp60 antibodies and serological markers of infection was observed, which may only indicate an indirect role of infection in the assessment of breaking the immunological tolerance against autologous HSPs.
4
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Interaction of the Pisum sativum nuc1ear matrix proteins with SAR DNA

75%
Rzepecki R., Markiewicz E., Adamiec R., Szopa J.
Acta Biochimica Polonica
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1995
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vol. 42
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issue 1
75-81
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