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EN
The study was aimed at testing whether the repetition priming was influenced by affective valence of visual stimuli. Neutral and emotionally negative words and images were shown in the right or in the left visual field. Each of the stimuli was repeated twice, with 2 to 4 other stimuli presented between repetitions. The subjects' task was detection of a stimulus. Responses were given by index finger of the left or right hand. The task was the same for all stimuli, the new and the repeated ones. Reaction times were measured and analyzed. The effects of repetition priming were significant only for neutral stimuli: repeated items were detected faster than the new ones. For emotionally negative items, generally no priming was observed. Interestingly, new emotionally negative stimuli were detected significantly faster in comparison to neutral stimuli. The results are discussed in relation to attentional processes involved in processing of affective stimuli.
EN
Cystic fibrosis (CF), the most common autosomal recessive disorder of Caucasians, is caused by the mutations in the gene encoding CFTR (Cystic Fibrosis Transmembrane Conductance Regulator) protein. Until now, approximately 1000 mutations of the CFTR gene have been described. The genotype-phenotype relationships in CF are still not completely understood. This study was undertaken in an attempt to characterise the distribution of CFTR mutations and their effect on selected clinical parameters in a group of Polish CF adults. A total number of 38 adult CF patients (mean age 21.6 ? 6.8); 18 females and 20 males were enrolled in the study. The CFTR gene identification was conducted with the use of PCR and InnoLipa-CF set. The assessed clinical parameters included: age at diagnosis, age, lung function test, X-ray scored in Brasfield score, weight & height. We found that: (1) the genotypes of the studied population were unevenly distributed (65.8% ? genotype deltaF508/M), (2) a high percentage of 3849+10kbC.T was noted, (3) patients homozygous for the deltaF508 mutation were diagnosed significantly earlier and had a lower body mass index, (4) no differences were observed in the patients? length of life or the progression of lung disease. Conclusions: 1. In comparison to other populations, Polish adult CF patients display a relatively higher frequency of mild mutations. 2. Late diagnosis of CF in the studied group may be partially caused by a high percentage of CFTR mutations connected with the mild course of the disease that are difficult to identify. 3. Cystic fibrosis should be more commonly taken into consideration in the differential diagnosis in adult patiens with milder symptoms.
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