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Activation of Salmonella-specific immune responses in the intestinal mucosa

100%

Srinivasan A., McSorley S. J.

Archivum Immunologiae et Therapiae Experimentalis

2006

vol. 54

issue 1

25-31

The mammalian immune response to Salmonella has long been a subject of scientific study. Indeed, many of the general aspects of bacterial pathogenesis and host immune defense have been well described. However, a lack of clarity remains concerning important aspects of the host immune response to Salmonella, particularly with regard to the induction of an immune response in the intestinal mucosa. A major limitation has been the general lack of knowledge about specific antigenic targets that are recognized by both the innate and adaptive immune response in the intestine. Progress towards the identification of these targets is critical for the development of a detailed model of immunity to Salmonella and will lead to a better understanding of mucosal immune responses to other intracellular pathogens.

Metallurgical Characterization of Hot Tearing Curves Recorded during Solidification of Magnesium Alloys

71%

Huang Y., Wang Z., Srinivasan A., Kainer K., Hort N.

Acta Physica Polonica A

2012

vol. 122

issue 3

497-500

This work investigates the hot tearing behavior of Mg-Al and Mg-Zn alloys quantitatively based on the measurement of contraction force using an experimental setup which was developed at MagIC. An emphasis is given on the analysis of typical hot tearing curves to understand the corresponding metallurgical phenomena shown by these curves. The recorded hot tearing curves, i.e. the contraction force vs. temperature or time, contain valuable metallurgical information. They give not only the precise temperature at which the hot tearing initiates, but also depict information about the propagation of hot cracks. Combined with thermodynamic calculations, the critical solid fraction corresponding to the occurrence of hot tearing can be calculated. Further microstructural observations were performed. Several phenomena such as the crack propagation and refilling of cracks, which influence the slope of hot tearing curves, are also discussed.

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1 Acta Physica Polonica A

1 Archivum Immunologiae et Therapiae Experimentalis

1 2012

1 2006

2 Srinivasan A.

1 Hort N.

1 Huang Y.

1 Kainer K.

1 McSorley S. J.

1 Wang Z.

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Activation of Salmonella-specific immune responses in the intestinal mucosa

Metallurgical Characterization of Hot Tearing Curves Recorded during Solidification of Magnesium Alloys