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4’, 6-diamidine-2-phenylindole (DAPI) preferentially inhibits poly A synthesis catalysed by bacterial RNA polymerase

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Wilmańska D., Ślaska-Kiss K., Gniazdowski M., Medical Academy of Łódź I. o. P. a. B.
Acta Universitatis Lodziensis. Folia Biochimica et Biophysica
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1988
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vol. 6
EN
This work was supported by the Polish Academy of Sciences within the project 09.7.
PL
4’,6-Diamidyno-2-fenyloindol (DAPI), związek wykazujący preferencją w stosunku do sekwencji typu dA: dT i wysokie powinowactwo do hybrydu poli rA: poli dT hamuje w znacznym stopniu syntezą poli A niż syntezą RNA katalizowaną in vitro przez zależną od DNA polimerazą RNA E. coli.
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