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Patient with metastatic renal cell carcinoma treated successfully with pazopanib for four years.

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Słowik A., Streb J., Chrzan R., Krzemieniecki K.
OncoReview
|
2015
|
vol. 5
|
issue 3
A109-116
EN
We present a case of a patient with metastatic renal cell carcinoma who was treated with pazopanib in the first-line treatment. Although nephrectomy was not performed, there was a positive reaction to the therapy with multi-targeted tyrosine kinase inhibitor. After 18 months of the palliative treatment, the cancerous kidney was surgically removed and pazopanib was restarted with the effect of further disease remission. The development of hypertension, complete hair discoloration and isolated hyperbilirubinemia occurred, and there was occasionally hypokalaemia in laboratory findings within 48 months of therapy. No serious adverse events were reported.
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