The activities of intercellular antioxidative enzymes: Superoxide dismutase, catalase and glutathione peroxidase were estimated in control and trisomic human fibroblasts in culture. It was found that in trisomic cells the activity of SOD is approximately 50% higher than in control cells. The activity of glutathione peroxidase is increased by 30% in trisomic fibroblasts, whereas catalase activity is similar in both types of cells.
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