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Lateral and median cysts of the neck

100%

Buła G., Waler J., Niemiec A., Mucha R., Gawrychowski J.

Polish Journal of Surgery

2012

vol. 84

issue 9

445-448

The aim of the study was to present clinical picture, indications for surgery, immediate and remote results of surgical treatment for lateral and median cysts of the neck. Material and methods. A total of 17247 patients were operated between 1 January 1990 and 31 December 2011 for neck tumors. Results. Neck cysts were diagnosed in 34 (0.2%) patients, including lateral in 12 (35.3%) and median in 22 (64.7%). Lateral cyst once descended to the mediastinal. Nodular goitres were diagnosed in 17 (50%) of them - with the lateral cysts 4x and median cysts 13x. Guided fine-needle aspiration biopsy of the cyst-like lesions revealed the presence of protein masses in all patients. The lesions were found to have inflammatory character in 6 patients (17.6%) regarding median cysts (5x) or lateral cyst (1x). Out of them, 3 patients developed purulent inflammatory process. All patients were operated. The operation consisted of radical resection of the cyst only or plus partial resection of both thyroid lobes and total resection of pyramidal lobe if concomitant goitre was found. Two patients required one-stage resection of the enlarged lymph nodes in the neck. Suspected focus of thyroid papillary cancer was found by intra-operative examination in neck median cyst wall in one patient. However, paraffin tests did not confirm the suspicion. Another patient was found by histopathological examination to have active tuberculotic process within both lateral cyst and lymph nodes. The patient received intensive antituberculotic treatment postoperatively. Conclusions. 1. Median cysts of the neck are more often accompanied by thyroid tumor-like goitres than lateral cysts. 2. Radical resection of the cysts in operative treatment results in good long term patient condition and prevent in recurrence of the illness.

Hospital physiotherapy after strumectomy

86%

Pasek J., Waler J., Waler N., Pasek T., Wiesztort M., Gawrychowski J., Sieroń A.

2010

vol. 18

issue 4

69-76

Współcześnie w medycynie coraz częściej obserwuje się wzrost zachorowań dotyczących gruczołu tarczowego. Choroby te występują kilkakrotnie częściej u kobiet niż u mężczyzn. Operacyjne usunięcie gruczołu tarczowego, niestety, nadal często stanowi jedyne skuteczne leczenie tego typu schorzeń. Zalecane jest ono najczęściej w przypadku chorych z olbrzymim wolem, z wolem dającym objawy uciskowe na narządy sąsiadujące oraz u chorych z wolem zawierającym guzki zimne (podejrzenie nowotworu złośliwego) lub autonomicznie nadczynne. Nieodzownym elementem leczenia powinno być wczesne uruchamianie chorego, stosowanie wybranych zabiegów i metod kompleksowej fizjoterapii. W pracy przedstawiono szpitalne postępowanie fizjoterapeutyczne przed i po zabiegu strumektomii, które stanowić powinno nieodłączny element leczenia pacjentów na oddziałach chirurgicznych.

The incidence rate of the thyroid gland diseases has been observed to grow at a increasing pace. Thyroid gland diseases occur more often (several times) in women than in men. Unfortunately, in many cases, surgical ablation of the thyroid gland is often the only way of effective treatment. Strumectomy is recommended for patients with gigantic goitre, with goiter giving compression symptoms on neighbouring organs, with goiter containing cold nodules (suspision of malignant neoplasm) or autonomous hyperfunction. It is vital for patients after strumectomy to be mobilized as early as possible after the operation and be subjected to selected procedures of comprehensive rehabilitation. This paper presents physiotherapeutic procedures employed in hospital rehabilitation before and after strumectomy, which the authors recognize as an indispensible element of treatment at surgical wards operating patients with thyroid gland diseases.

JunGene Expression is Decreased in Parathyroid Adenoma

59%

Żebracka-Gala J., Waler J., Gawrychowski J., Hasse-Lazar K., Kowalska M., Niemiec A., Szpak-Ulczok S., Jurecka-Lubieniecka B., Buła G., Truchanowski W., Gubała E., Jarząb B.

issue 10

457-464

The aim of the study was to analyze the gene expression of JUN and CCND1 in a group of parathyroid tissues obtained from patients with primary hyperparathyroidism in comparison to hyperplastic parathyroid and normal/atrophic parathyroid tissues by real-time quantitative PCR. Our goal was to validate the conclusion of Forsberg et al (2005) who reported overexpression of JUN in parathyroid adenomas by a joint microarray and QPCR study.Material and methods. The analysis of JUN, CCND1 was carried out by QPCR in 14 parathyroid adenomas, 8 hyperplasia cases and 50 normal/atrophic parathyroid samples taken intraoperatively. Expression of the examined genes was normalized to the reference index (geometric mean of reference genes expression: EIF3S10, UBE2D2, ATP6V1E).Results. We observed a decrease of JUN expression in parathyroid adenomas in comparison to both normal/atrophic and hyperplastic parathyroids. The fold change value was 0.71 in comparison of adenomas to normal/atrophic samples (p = 0.044) and 0.75 to hyperplastic glands (p = 0.003). For CCND1 we observed one case of parathyroid adenoma with a very clearly increased expression, while 3 adenomas (21.4% of all adenomas) exhibited the increase over the highest value seen in normal parathyroids (fold change = 3.52).Conclusions. In parathyroid adenomas we were not able to confirm any overexpression of JUN gene, as suggested by the previous study. On the contrary, we observed a distinct inhibition of JUN RNA expression in comparison to non-neoplastic parathyroids. For CCND1 gene overexpression in parathyroid adenomas, we report the frequency of 21.4%.

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2 Polish Journal of Surgery

1 Physiotherapy

1 2012

1 2010

1 2009

3 Gawrychowski J.

3 Waler J.

2 Buła G.

2 Niemiec A.

1 Gubała E.

1 Hasse-Lazar K.

1 Jarząb B.

1 Jurecka-Lubieniecka B.

1 Kowalska M.

1 Mucha R.

1 Pasek J.

1 Pasek T.

1 Sieroń A.

1 Szpak-Ulczok S.

1 Truchanowski W.

1 Waler N.

1 Wiesztort M.

1 Żebracka-Gala J.

Search results

Lateral and median cysts of the neck

Hospital physiotherapy after strumectomy

JunGene Expression is Decreased in Parathyroid Adenoma