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P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, and cancer growth and metastasis

100%

Chen M., Geng J.-G.

Archivum Immunologiae et Therapiae Experimentalis

2006

vol. 54

issue 2

75-84

Stimulated endothelial cells and activated platelets express P-selectin (CD62P), a member of the selectin family of cell adhesion molecules, which interacts with P-selectin glycoprotein ligand-1 (PSGL-1, CD162) for leukocyte rolling on stimulated endothelial cells and heterotypic aggregation of activated platelets onto leukocytes. Cross-linking of PSGL-1 by P-selectin also primes leukocytes intracellularly for cytokine and chemoattractant-induced 2-integrin activation for firm adhesion of leukocytes. Furthermore, P-selectin mediates heterotypic aggregation of activated platelets to cancer cells and adhesion of cancer cells to stimulated endothelial cells. Here we provide a comprehensive summary of the functional roles and the biological importance of P-selectin-mediated cell adhesive interactions in the pathogeneses of inflammation, thrombosis, and the growth and metastasis of cancers.

Raman Spectroscopy of LiFePO_4 and Li_3V_2(PO_4)_3 Prepared as Cathode Materials

61%

Ziółkowska D., Korona K., Kamińska M., Grzanka E., Andrzejczuk M., Wu S., Chen M.

Acta Physica Polonica A

2011

vol. 120

issue 5

973-975

Structure of samples of lithium iron vanadium phosphates of different compositions were investigated by X-rays, electron microscopy and Raman spectroscopy. The investigated salts were mainly of olivine-like and NASICON-like structures. The X-ray diffraction and the Raman scattering show different crystalline structures, which is probably caused by difference between cores of the crystallites (probed by X-rays) and their shells (probed by the Raman scattering). Most of the Raman spectra were identified with previously published data, however in the samples with high vanadium concentration we have observed new, not reported earlier modes at 835 cm^{-1} and 877 cm^{-1}, that we identified as oscillations related to V_2O_7^{4-} or VO_4^{3-} anions.

Genotyping and pathogenic characterization of canine distemper virus based on mutations in the hemagglutinin gene in Chinese domestic dogs

52%

Chen M., Xin T., Hou S., Lin W., Song W., Zhu H., Huang K., Jia H.

Polish Journal of Veterinary Sciences

2018

vol. 21

issue 3

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1 Acta Physica Polonica A

1 Archivum Immunologiae et Therapiae Experimentalis

1 Polish Journal of Veterinary Sciences

1 2018

1 2011

1 2006

3 Chen M.

1 Andrzejczuk M.

1 Geng J.-G.

1 Grzanka E.

1 Hou S.

1 Huang K.

1 Jia H.

1 Kamińska M.

1 Korona K.

1 Lin W.

1 Song W.

1 Wu S.

1 Xin T.

1 Zhu H.

1 Ziółkowska D.

Search results

P-selectin mediates adhesion of leukocytes, platelets, and cancer cells in inflammation, thrombosis, and cancer growth and metastasis

Raman Spectroscopy of LiFePO_4 and Li_3V_2(PO_4)_3 Prepared as Cathode Materials

Genotyping and pathogenic characterization of canine distemper virus based on mutations in the hemagglutinin gene in Chinese domestic dogs