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About toxic effects of platinum anticancer drugs

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Waszkiewicz K.
Postępy Higieny i Medycyny Doświadczalnej
|
2001
|
vol. 55
|
issue 3
387-406
EN
The work present current view about toxic effects of platinum anticancer drugs. In the first part, the toxic effects of cisplatin as nephrotoxicity, ototoxicity, myelosuppression, anaphylacticlike reactions, neurotoxicity and gastrotoxicity are presented. The second part describes mechanisms of cisplatin. The third part, the toxicity of carboplatin and iproplatin are reviewed.
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