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Evaluation of Gingival Conditions and Saliva TNF-α Concentration in Children with Acute Lymphoblastic Leukemia

100%
Pels E.
Polish Journal of Public Health
|
2015
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vol. 124
|
issue 2
81-85
EN
Introduction. Patients with the history of neoplastic disease in childhood and adolescence, successfully treated, are at higher risk in terms of their susceptibility to develop other diseases later in their lives. Aim. The purpose of study was to evaluate saliva TNF-α concentration in the children with acute lymphoblastic leukemia with reference to gingival inflammations. Material and methods. The investigation was carried out in the group of 78 children with ALL aged 2-18yrs and analogical in terms of age and gender group of healthy controls. Results. Gingival conditions were expressed as gingival index (GI). In the group of children with ALL mean GI determined in examination 1 was 0.084±0.34, in examination 2 GI=0.007±0.04 and in examination 3 mean GI=0.017±0.13. In the group of healthy controls GI=0.003±0.03. Saliva concentration of TNF-α determined in the group of children with ALL in examination 1 ranged 4.16-135.01pg/ml. In that group in examination 1, mean saliva TNF-α concentration was 36.9±32.6pg/ml. In the group of healthy children mean saliva TNF-α concentration was 52.1±107.64pg/ml. Conclusions. The authors, who observed various increases in the concentrations of TNF-α, IL-1α, IL-6, and IL-8 in the saliva and oral tissues in the patients consider that the proinflammatory cytokines in the saliva present in significantly higher concentrations in the future may have diagnostic and predicative value as replace indices of neoplastic transformations. Monitoring of prognostic factors affecting inflammations of the oral mucosa in children with ALL is likely to prevent complications to standard treatment and prolonged time of anticancer therapy. Early evaluation of those parameters can quicken recovery and strengthen patient's health. Close cooperation between dentists and pediatricians-hematologists is important in maintaining oral health and improve the quality of life of children suffering from neoplastic diseases.
2
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Composite Inlays as A Modern Way of Posterior Restorations in the Dental Arch

51%
Chałas R., Jurczykowska M., Marczyński R., Pels E.
Polish Journal of Public Health
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2015
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vol. 124
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issue 2
99-102
EN
Modern restorative dentistry offers many methods of restoring qualitative cavities within the clinical crowns. Due to the concept of maintaining continuity of the dental arch and maintaining the correct plane of occlusion, for reconstruction of posterior teeth, there are especially recommended indirect restorations, which are made in the dental laboratory, i.e. crown inlays. The aim of the study was based on the literature to describe indications, classifications and advantages of indirect composite inlays. Additionally, factors affecting the durability of indirect composite inlays and the influence on stomatognathic system were noted. Authors concluded that composite inlays can be recommended restoration method, not only in situations of loss of clinical crown tissue, but also in situations where it is necessary as structural reinforcement, e.g., in the case of Cracked Tooth Syndrome or Molar Incisor Hypomineralization.
3
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Therapeutic management of an injury of the upper incisor within complete root formation

39%
Mielnik-Błaszczak M., Struska A., Rudnicka-Siwek K., Warsz M., Stachurski P., Pels E., Wróbel R.
Current Issues in Pharmacy and Medical Sciences
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2015
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vol. 28
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issue 4
283-284
EN
A 9.5 year-old patient, following an accident, suffered a comminuted lateral fracture of the root of tooth 21 at the neck level. The treatment consisted of immobilizing and maintaining tooth vitality. The presented case provides a basis for the conclusion that premature radical, surgical and endodontic actions should not always be performed.
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