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EN
Autonomic impairment is associated with poor progno in many diseases.The article critically reviews arguments found in the literature showing autonomic dysfunction in chronic renal failure patients.The autonmic nervous system problems will become of great clinical relevance considering increasing number and age of uremic patients being dialysed worlwide.
EN
Autonomic impairment is associated with poor prognosis in many diseases.The pathogenesis of the uremic autonomic neuropathy has not been convincingly established, so the article reviews available information on factors involved in its development, futhermore the autors put forward their own hypothetical scheme of the pathogenesis.The last section outlines the methods most commonly used for its diagnosis and finally the autors discuss symptoms suggestive of this neuropathy in clinical setting.
EN
The autonomic impairment, which is the frequent complication of end-stage renal failure, may eventually trigger numerous cripping consequences.It is doubtful if standard dialysis techiques may effectively treat once developed autonomic lesions.Renal transplantation seems to be much more efficient.The article points out the discrepancies in symptoms attributable to autonomic impairment and results of autonomic testing, discussed also differences between somatic and autonomic nervous system involvement in uremic patients.The one of the most important part of the article describes the practical approach to the patient with severely symptomatic uremic autonomic neuropathy.Finally the autors articulate their proposals for further research on uremic autonomic neuropathy.
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