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1

Commentary on: The usefulness and limitations of diffusion tensor imaging – a review study

100%

Szmuda T., Ali S.

European Journal of Translational and Clinical Medicine

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2020

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vol. 2

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issue 2

85-86

2

Commentary on: The usefulness and limitations of diffusion tensor imaging – a review study

100%

Szmuda T., Ali S.

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2019

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vol. 2

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issue 2

85-86

EN

not relevant for commentary

3

Changing paradigms in breast cancer treatment

81%

Ali S., Buczek D., Jassem J.

European Journal of Translational and Clinical Medicine

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2020

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vol. 3

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issue 2

53-63

EN

In only the past century, the landscape of breast cancer treatment has completely changed. The Halstedian hypothesis of the “contiguous spread” of breast cancer has been replaced by a consideration of its systemic nature. Today, patients with early-stage breast cancer are managed with breast-conserving therapy, which is as effective as mastectomy. Sentinel lymph node biopsy has largely replaced axillary lymph node dissection. Post-operative radiotherapy, chemotherapy and endocrine therapy have increased survival. Pre-operative cytotoxic therapy allows for less extensive surgery and for a curative resection even in more advanced stages. Rapid progress in molecular oncology revealed a large heterogeneity of breast cancer, resulting in a more personalized approach. Targeted therapies directed against epidermal growth factor receptor type 2 (HER2) have improved survival in HER2-positive breast cancer, which was once a poor-prognosis entity. Multi-gene prognostic signatures better predict prognosis and allow many patients to avoid chemotherapy. Personalized treatment has resulted in decreased toxicity and an improved quality of life. Within the past decades, breast cancer has become a good-prognosis malignancy with a five-year survival in the range of 80-85%. Future development of personalized medicine may further refine treatment based on the tumor’s molecular features.

4

How to write a scientific paper? Lessons from a distinguished scientist and editor

81%

Ali S., Szmuda T., Wszołek Z.

European Journal of Translational and Clinical Medicine

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2020

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vol. 3

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issue 1

74-78

EN

This article is an instructive guide on how to write and publish a scientific article. It was inspired by a lecture given at the Medical University of Gdańsk by a distinguished professor. To further advance science, particularly in the currently emerging era of individualized medicine, the collaboration of researchers with a varied level of experience and from different areas of expertise is needed. It is vital to publish the results of research quickly and effectively. Knowing the basic mechanisms of writing and publishing will help to disseminate research results more effectively.

5

Sciatica: Internet Search Trends

81%

Szmuda T., Ali S., Czyz M., Słoniewski P.

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2020

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vol. 3

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issue 1

49-52

EN

Background Sciatica carries a significant health burden in the world as the lifetime incidence of sciatica estimated between 13% to 40%. We used modern scientific tools to assess the online health interest of sciatica and lower back pain. Material and methods Google Trends, Wikipedia statistics and PubMed data were used to gauge the online public interest in sciatica and lower back pain. Results Over the last five years, (2015–2019) the Wikipedia page for sciatica has ranked high in all four categories it was included in; this shows that sciatica is a major concern for the public. Wikipedia page views on sciatica and low back pain show a 28% and 90% increase respectively from July 2015 to March 2019. In the last eleven years (2008–2019) Google Trends shows that sciatica has had a 2-fold increase in search frequency worldwide on the web, a 6-fold increase on YouTube and a 3-fold increase on Google images. Scientific interest in sciatica is low (only 140 PubMed publications in 2018). Conclusions The public has a relatively high online interest concerning sciatica and back pain and this interest is rising. We suggest that hospitals clearly address the causes, pathophysiology, and management of sciatica to their patients to account for this increase.

6

Sciatica: Internet Search Trends

81%

Szmuda T., Ali S., Czyz M., Słoniewski P.

European Journal of Translational and Clinical Medicine

|

2020

|

vol. 3

|

issue 1

49-52

EN

Background: Sciatica carries a significant health burden in the world as the lifetime incidence of sciatica estimated between 13% to 40%. We used modern scientific tools to assess the online health interest of sciatica and lower back pain. Material and methods: Google Trends, Wikipedia statistics and PubMed data were used to gauge the online public interest in sciatica and lower back pain. Results: Over the last five years, (2015–2019) the Wikipedia page for sciatica has ranked high in all four categories it was included in; this shows that sciatica is a major concern for the public. Wikipedia page views on sciatica and low back pain show a 28% and 90% increase respectively from July 2015 to March 2019. In the last eleven years (2008–2019) Google Trends shows that sciatica has had a 2-fold increase in search frequency worldwide on the web, a 6-fold increase on YouTube and a 3-fold increase on Google images. Scientific interest in sciatica is low (only 140 PubMed publications in 2018). Conclusions: The public has a relatively high online interest concerning sciatica and back pain and this interest is rising. We suggest that hospitals clearly address the causes, pathophysiology, and management of sciatica to their patients to account for this increase.

7

How to write a scientific paper? Lessons from a distinguished scientist and editor

81%

Ali S., Szmuda T., Wszołek Z.

|

2020

|

vol. 3

|

issue 1

74-78

EN

Background This editorial is an instructive guide on how to write and publish a scientific paper. It was inspired by a lecture given at the Medical University of Gdańsk by a distinguished professor. To further advance science, particularly in the currently emerging era of individualized medicine, the collaboration of researchers with a varied level of experience, and from different areas of expertise is needed. It is vital to publish the results of research quickly and effectively. Knowing the basic mechanisms of writing and successful publication will assist in more effective dissemination of research results. Material and methods N/A Results N/A Conclusions N/A

8

Changes in the neurosurgical admissions during the COVID-19 pandemic – a comparison with 2019

61%

Fercho J., Szmuda T., Ali S., Szplit D., Jurkiewicz A., Słoniewski P., Stefaniak T.

European Journal of Translational and Clinical Medicine

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2021

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vol. 4

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issue 1

22-28

EN

Background: The coronavirus pandemic has strongly affected health-care systems around the world, testing their patients’ care capacities. Admission restrictions, patients’ fear of hospitalization or other uncomprehended constraints has affected admissions to neurosurgery department. Material and methods: The clinical data of admissions from March 1st to July 24th 2020, as well as data of the control group in relevant periods of time in 2019 was collected from the local hospital database and compared. Results: The total number of procedures performed between March and July 2020 is 1545, compared to the corresponding period of the previous year it was the number of 2062, indicating a decrease by about 25%. Both head and aneurysm procedures decreased over the entire analyzed period. The number of procedures classified as "other" was higher in each of the three stages. Between March 1st and April 30th (Phase 1) mainly younger male patients were admitted. Conclusions: We demonstrated the impact of the COVID-19 pandemic on the work organization of our Neurosurgery Department. We report that after the introduction of appropriate solutions, it is possible to provide care to neurosurgical patients while ensuring the safety of patients and Staff during the pandemic.

9

In the midst of imbalance: medical and healthcare students versus SARS-CoV-2

52%

Kamieniecki A., Marek D., Dułak N. A., Skrzypkowska P., Louise Olofsson H. K., Szmuda T., Słoniewski P., Ali S.

European Journal of Translational and Clinical Medicine

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2021

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vol. 5

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issue 2

42-52

EN

Background During the COVID-19 era, it is crucial to determine the level of relevant infectious disease knowledge amongst medical students as they may influence public opinion by acting as informal medical advisors to their friends and family. We sought to assess the knowledge of students regarding COVID-19 at a single Polish medical university, to understand the level of knowledge and determine if dedicated COVID-19 education is necessary. Material and methods The survey was conducted in Google Forms and access was obtained through the university’s secure email. After exclusion, 1.001 students were enrolled. Results The most common mask used amongst students is a surgical mask. Regarding SARS-CoV-2 transmission, 79,1% chose droplet and 19,3% chose airborne transmission. Only 35% agreed that surgical masks protect them from coronavirus and 70% strongly agreed or agreed that all healthcare workers should wear an N95/FFP3 mask. Students with a healthcare worker in the family more likely agreed that all healthcare workers should wear N95/FFP3 (p = 0.001). The source of information used affected the route of transmission chosen (p = 0.006). Conclusions We recommend combatting contradicting information by healthcare students having dedicated education on SARS-CoV-2, PPE, filtering efficiency of masks, modes of transmission of viruses, and how to use evidence-based medicine for better public health dispersion.

10

Datasets and future research suggestions concerning SARS-CoV-2

28%

Szmuda T., Ali S., Özdemir C., Syed M. T., Singh A., Hetzger T. V., Rosvall P., Fedorow K., Alkhater A., Majlöf A., Albrahim M., Alquraya E., Dunquwah R. A., Al-hakeem Z., Almohisin E., Alradhi M., Żydowicz W. M., Müller C., Egeland A., Bergersen Kinstad A., Ngyuen J., Bergersen Kinstad M., Al-Rubaye I., Al-Khazragi Y., von Dardel B., Dave B., Słoniewski P., Fercho J., Kierońska S.

European Journal of Translational and Clinical Medicine

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2020

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vol. 3

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issue 2

80-85

EN

We gathered publicly available online data and prepared a database of epidemiology, demographics, economics, Bacille Calmette-Guérin vaccination and online search trend statistics relevant to the coronavirus disease 2019 (COVID-19). Moreover, we provide several suggestions on the use of this bioresource and reference other relevant datasets to promote research on COVID-19.

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Commentary on: The usefulness and limitations of diffusion tensor imaging – a review study

Commentary on: The usefulness and limitations of diffusion tensor imaging – a review study

Changing paradigms in breast cancer treatment

How to write a scientific paper? Lessons from a distinguished scientist and editor

Sciatica: Internet Search Trends

Sciatica: Internet Search Trends

How to write a scientific paper? Lessons from a distinguished scientist and editor

Changes in the neurosurgical admissions during the COVID-19 pandemic – a comparison with 2019

In the midst of imbalance: medical and healthcare students versus SARS-CoV-2

Datasets and future research suggestions concerning SARS-CoV-2