Search results

Sort By:

Limit search:

Glutamate receptors in the central nervous system

100%

Kolonko A.

Postępy Higieny i Medycyny Doświadczalnej

1995

vol. 49

issue 6

719-731

A lot of clinical processes following excessive stimulation of glutamate receptors seem to participate in pathophysiology of numerous acute and chronic neurologicla disorders.The whole of these reactions has been named as "glutamate cascade", because of the central role of glutamate in initiation and intensification of these processes.In this article, classification of different types of glutamate receptors and several hypotheses concerning mechanisms of glutamate neurotoxic activity are presented.A wide variety of neurological diseases, which etiologies are more or less connected with glutamate toxicity are discussed. At last, the future perspecives for treatment by drugs which action is though to be mediated through glutmate receptord are persented.

Contrast-induced nephropathy - etiology and prevention

51%

Kolonko A., Wiecek A., Kokot F.

Postępy Higieny i Medycyny Doświadczalnej

1996

vol. 50

issue 3

245-263

Contrast-induced nephropathy remains one of the most serious adverse event of contrast imaging. Patients with existing renal impairment, with or without diabetes, those with congestive heart failure or myeloma, and patients who receive nonsteroidal antyinflammatory drugs may be at higher risk. The pathogenesis of contrast-induced nephrotoxicity probably involves renal ischemic injury, tubular obstruction and direct tubular toxicity. Some prophylactic procedures based on these pathogenetic hypotheses have been proposed. Up-to-date knowledge on incidence, pathogenesis, risk factors, preventive procedures and therapeutic approaches of radiocontrast nephropathy is reviewed

Refine search results

2 Postępy Higieny i Medycyny Doświadczalnej

1 1996

1 1995

2 Kolonko A.

1 Kokot F.

1 Wiecek A.

Search results

Glutamate receptors in the central nervous system

Contrast-induced nephropathy - etiology and prevention