Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 5

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Content available remote

Nanospray mass spectrometry for identification of peptides. Application of a novel interface

100%
Smoluch M. T., Sällberg M., Silberring J.
Acta Biochimica Polonica
|
1999
|
vol. 46
|
issue 2
475-481
2
Content available remote

Hematological and antifungal properties of temporin A and a cecropin A-temporin A hybrid.

76%
Wade D., Silveira A., Rollins-Smith L., Bergman T., Silberring J., Lankinen H.
|
2001
|
vol. 48
|
issue 4
1185-1189
EN
Temporin A (TA) and a cecropin A-temporin A hybrid peptide (CATA) were synthesized and assayed for their hemolytic, anticoagulant, and antifungal properties. CATA retains significant antifungal activity, is less hemolytic than TA, and inhibits blood coagulation. These results recommend further studies of the biological activities of CATA.
3
Content available remote

Search for new synthetic immunosuppressants II. Tetrazole analogues of hymenistatin I.

76%
Zubrzak P., Kociołek K., Smoluch M., Silberring J., Kowalski M. L., Szkudlińska B., Zabrocki J.
|
2001
|
vol. 48
|
issue 4
1151-1154
EN
Linear and cyclic hymenistatin I (HS I) analogues with dipeptide segments Ile2-Pro3, Pro3-Pro4 and Val6-Pro7 replaced by their tetrazole analogues Ile-Ψ[CN4]-Ala3, Pro3-Ψ[CN4]-Ala4 and Val6-Ψ[CN4]-Alawere synthesized by the solid phase peptide synthesis method and cyclized with the TBTU and/or HATU reagent. The peptides were examined for their immunosuppressive activity in the lymphocyte proliferation test (LPT).
4
Content available remote

FAPA mass spectrometry of hydroxychalcones. Comparative studies with classical methods of ionization

76%
Smoluch M., Bartkowiak G., Reszke E., Lechowicz W., Silberring J., Schroeder G.
Current Issues in Pharmacy and Medical Sciences
|
2014
|
vol. 27
|
issue 1
27-31
EN
In this paper we are focused on analysis of hydroxychalcones, i.e. 2’-hydroxychalcone, 3’-hydroxychalcone and 4’-hydroxychalcone, by the Flowing Atmospheric Pressure Afterglow mass spectrometry (FAPA-MS), and on comparison of the obtained data with other classical methods including ESI-MS, APCI, MALDI, and GC/EI-MS. The paper is presenting fragmentation pathways of both positive-, and negative hydroxychalcone ions. Tested compounds were characterized by comparison of the results (signals m/z and relative intensities) from the five mass spectrometry techniques, showing very good utility of FAPA method for fast and easy analysis of the low molecular weight compounds. Moreover, FAPA does not require a time-consuming derivatization, nor search for a suitable solvent or matrix, often incompatible with various ion sources.
5
Content available remote

Desorption/ionization on silicon for small molecules: a promising alternative to MALDI TOF.

76%
Kraj A., Dylag T., Gorecka-Drzazga A., Bargiel S., Dziuban J., Silberring J.
|
EN
A method has been developed for laser desorption/ionization of catecholamines from porous silicon. This methodology is particularly attractive for analysis of small molecules. MALDI TOF mass spectrometry, although a very sensitive technique, utilizes matrices that need to be mixed with the sample prior to their analysis. Each matrix produces its own background, particularly in the low-molecular mass region. Therefore, detection and identification of molecules below 400 Da can be difficult. Desorption/ionization of samples deposited on porous silicon does not require addition of a matrix, thus, spectra in the low-molecular mass region can be clearly readable. Here, we describe a method for the analysis of catecholamines. While MALDI TOF is superior for proteomics/peptidomics, desorption/ionization from porous silicon can extend the operating range of a mass spectrometer for studies on metabolomics (small organic molecules and their metabolites, such as chemical neurotransmitters, prostaglandins, steroids, etc.).
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.