Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl
Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 5

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Publication available in full text mode
Content available

New compensation scheme of magneto-optical current sensor for temperature stability improvement

100%
Chen J., Li H., Zhang M., Zhang Y.
Metrology and Measurement Systems
|
2012
|
issue 3
2
Content available remote

The influence of spontaneously generated coherence on atom-photon entanglement in a Λ-type system with an incoherent pump

88%
Yang X., Yan D., Bao Q., Zhang Y., Cui C.
Open Physics
|
2014
|
vol. 12
|
issue 12
813-821
EN
Owing to interference induced by spontaneous emission, the density-matrix equations in a three-level Λ-type system have an additional coherence term, which plays a critical role in modulating the inversionless gain and electromagnetically induced transparency effect. In addition, it is shown that spontaneously generated coherence (SGC) has an effect on the entanglement between an atom and a photon of the coupling laser field by calculating the degree of entanglement (DEM) of the atomic system. In this paper, we investigate the influence of the SGC effect on atom-photon entanglement in a Λ-type system, which generally remains a high entangled state. When an incoherent pump source is introduced, we find that the SGC effect could exert considerable influence on the atom reduced entropy under certain conditions for both transient and steady states. More interestingly, such an incoherent pump field could actively affect the short-time dynamic behaviors of the transient quantum entangled state at a certain range of pump rate as a typical coherent case.
3
Content available remote

pVAX1 plasmid vector-mediated gene transfer of soluble TRAIL suppresses human hepatocellular carcinoma growth in nude mice

88%
Zhang Y., Ma C. H., Liu H., Zhang X. M., Sun W. S.
|
2007
|
vol. 54
|
issue 2
307-313
EN
The extracellular domain of the tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) may function as a soluble cytokine to selectively kill various cancer cells without toxicity to most normal cells. We used a high-biosafety plasmid pVAX1 as a vector and constructed a recombinant plasmid expressing the extracellular domain (95-281 aa) of human TRAIL fused with signal peptides of human IgGγ, designated as pVAX-sT. Transduction of human BEL7402 liver cancer cells with pVAX-sT led to high levels of sTRAIL protein in the cell culture media and induced apoptosis. The therapeutic potential of pVAX-sT was then evaluated in the BEL7402 transplanted naked mouse model. Subsequent intratumoral administration of naked pVAX-sT resulted in the expression of soluble TRAIL in the sera and the tumor site, as well as effective suppression of tumor growth, with no toxicity to liver. In conclusion, the successful inhibition of liver cancer growth and the absence of detectable toxicity suggest that pVAX-sT could be useful in the gene therapy of liver cancer.
4
Content available remote

Various evaluations of a diffractive transmitted field of light through a one-dimensional metallic grating with subwavelength slits

88%
Hu B., Gu B.-Y., Dong B.-Z., Zhang Y., Liu M.
Open Physics
|
2010
|
vol. 8
|
issue 3
448-454
EN
We compare the Fresnel-Kirchhoff diffraction formula, the superposition of cylindrical waves, and the twodimensional (2D) Green’s function diffraction formula with a rigorous vector algorithm in calculating the near and intermediately transmitted field of light through a one-dimensional metallic grating with subwavelength slits. It is found that the results calculated by the 2D Green’s function diffraction formula coincide well with the precise result. The other evaluations deviate from the exact result by varying proportions. Our findings may provide a useful and precise way to analyze the transmitted field features of a metallic grating and subsequent possibility of achieving optimal designs for metallic optical elements with subwavelength scale.
5
Content available remote

Two Gln187 mutants of human soluble APRIL inhibit proliferation of lung carcinoma A549 cells

64%
Dai S., Zheng Y., Chen B., Gao M., Zhang Y., Zhang L., Gong W., He F.
|
|
issue 4
703-710
EN
Soluble APRIL (sAPRIL), the active form of a proliferation-inducing ligand (APRIL), is implicated in the proliferation of tumor cells. Suppressing APRIL function has been considered as a potential strategy for the therapy of APRIL-associated tumors. In the present study, we generated human sAPRIL and its two mutants, Gln187-D-sAPRIL (Gln187 deleted) and Gly187-sAPRIL (Gln187 replaced by Gly). In vitro experiments showed that the two mutants had similar specific binding capacity to lung carcinoma A549 cells compared to the wild-type sAPRIL, and both, especially Gly187-sAPRIL, exhibited significant antagonistic effect on sAPRIL-induced tumor cell proliferation in a dose-dependent manner, which might be predominantly mediated by blocking sAPRIL-induced MEK and ERK phosphorylation but not p38MAPK or JNK signaling. In vivo experiments with nude mice bearing A549 cell-derived xenograft tumor showed that only the Gly187-sAPRIL mutant could significantly suppress the tumor growth. These results suggest that Gln187 may be a crucial amino acid in APRIL-mediated tumor cell proliferation via the MEK-ERK signaling pathway and that the sAPRIL mutants may serve as novel potential antagonists of APRIL for the therapy of APRIL-associated cancers.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.