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1

Neuroprotective effects of ginsenosides

100%

Rausch W.-D., Liu S., Gille G., Radad K.

Acta Neurobiologiae Experimentalis

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2006

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vol. 66

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issue 4

369-375

EN

Ginseng, the root of the Panax species, is a well-known herbal medicine. Traditionally it has been used in Korea, China and Japan for thousands of years. Nowadays it has become a popular and worldwide known health drug. Current scientific studies demonstrate in vivo and in vitro its beneficial effects in a wide range of pathological conditions such as cardiovascular disease, cancer, immune deficiency and hepatotoxicity. Ginsenosides or ginseng saponins as the active ingredients have antioxidant, anti-inflammatory, anti-apoptotic and immunostimulant properties, which raised speculations that these compounds could positively affect neurodegenerative disorders and delay neuronal aging. Conclusive clinical data in humans are still missing. However, results from animal studies and neuronal cell culture experiments indicate that ginsenosides can counteract and attenuate factors promoting neuronal death as environmental toxins, excitotoxic action of glutamate and rises in intracellular calcium, excessive release of free radicals and apoptotic events. Thus, neuroprotective actions of ginsenosides could come about as a valuable option to slow down neurodegenerative diseases.

2

Effect of Strain Rate on the Microstructure of Warm-Deformed Ultrafined Medium-Carbon Steel

88%

Yuan Q., Xu G., Liu S., Liu M., Hu H.

Archives of Metallurgy and Materials

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2018

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vol. 63

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issue 4

3

Neurons derived from PC12 cells have the potential to develop synapses with primary neurons from rat cortex

76%

Zhou T., Xu B., Que H., Lin Q., Lv S., Liu S.

Acta Neurobiologiae Experimentalis

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2006

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vol. 66

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issue 2

105-112

EN

Neuron transplantation is considered to be a promising therapeutic method to replace functions lost due to central nervous system (CNS) damage. However, little is known about the extent to which implanted neuron-like cells can develop into mature neurons and acquire essential properties, and especially form synapses with host neurons. In this investigation we seeded PC12 cells labeled with GFP into primary cultured neurons isolated from rat cerebral cortex to build a co-culture system, and then induced the PC12 cells to differentiate into neuron-like cells with NGF. Seven days later, we observed the relationship between the PC12-derived neurons and primary neurons using FM1-43 imaging and immunoelectron microscopy, and found that GFP-labeled neurons could form typical synapses with host primary neurons. These observations showed that immigrant neurons differentiated from PC12 cells could develop into mature neurons and could form intercellular contacts with host neurons. Both the immigrant and host neurons could construct neuronal networks in vitro.

4

Effect Of The Desorption-Recombination Temperature On The Microstructure And Magnetic Properties Of HDDR Processed Nd-Fe-B Powders

76%

Lee J.-G., Liu S., Cha H.-R., Yu J.-H., Baek Y.-K., Kwon H.-W.

Archives of Metallurgy and Materials

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2015

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issue 2

5

Biological characteristics of a new antibacterial peptide and its antibacterial mechanisms against Gram-negative bacteria

52%

Pei Z., Ying X., Tang Y., Liu L., Zhang H., Liu S., Zhang D., Wang K., Kong L., Gao Y., Ma H.

Polish Journal of Veterinary Sciences

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2018

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vol. 21

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issue 3

Refine search results

Neuroprotective effects of ginsenosides

Effect of Strain Rate on the Microstructure of Warm-Deformed Ultrafined Medium-Carbon Steel

Neurons derived from PC12 cells have the potential to develop synapses with primary neurons from rat cortex

Effect Of The Desorption-Recombination Temperature On The Microstructure And Magnetic Properties Of HDDR Processed Nd-Fe-B Powders

Biological characteristics of a new antibacterial peptide and its antibacterial mechanisms against Gram-negative bacteria