Wstęp: Jednym z niekorzystnych następstw radykalnej mastektomii jest obrzęk limfatyczny kończyny górnej (OLKG). Mechanizm jego powstawania nie jest do końca wyjaśniony. U części chorych wskazuje się na predyspozycje konstytucjonalnych operowanych. Istniejące parametry somatyczne mogące być przydatnymi w szacowaniu ryzyko rozwoju OLKG rzadko są jednak przedmiotem longitudinalnych pooperacyjnych obserwacji. Cel badań: Celem badań było prześledzenie zmian wybranych parametrów somatycznych u kobiet z OLKG i bez OLKG w trakcie pooperacyjnej obserwacji po amputacji piersi. Materiał i metody: Analizie poddano 45 kobiet, u których wystąpił OLKG po radykalnej mastektomii. W tej grupie chorych jak również w grupie kontrolnej (41 kobiet bez OLKG) dokonano analizy zmian masy ciała oraz wskaźnika BMI, Rohrera, Queteleta i Pigneta-Verwaecka. Parametry te oceniano przed zabiegiem jak równieŜ w okresie 5 – letniej pooperacyjnej obserwacji. Wyniki: Stwierdzono, że przez cały czas trwania kontrolnych badań longitudinalnych średnie wartości masy ciała oraz wskaźnika Rohrera, Queteleta i Pigneta-Verwaecka. Znamienne statystycznie różnicowały grupę kobiet z OLKG od grupy bez obrzęku. Jedynie średnie wartości wskaźnika BMI od 30. miesiąca po zabiegu były porównywalne dla obu grup kobiet. Wniosek: Wykazano, że pomimo wydłużania okresu obserwacji, badane parametry antropometryczne (z wyjątkiem BMI) nie tracą swego przedoperacyjnego znaczenia czynników różnicujących w sposób istotny statystycznie grupy kobiet z OLKG od kobiet bez tego powikłania.
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Introduction: Lymphoedema of the upper limb (ULL) is one of the most unfavorable sequels of radical mastectomy. Mechanism of its formation is not completely elucidated. In some patients, constitutional predispositions of the operated women are considered responsible for lymphoedema formation. The existing somatic parameters may be useful in determining the risk of ULL development, however they are rarely addressed in longitudinal post-operative observations.Purpose of the study: The aim of the study was to observe changes in selected somatic parameters in women with and without ULL during post-operative follow-up after breast amputation.Material and method: The analysis comprised 45women, in whom ULL occurred after radical mastectomy. In this group of patients as well as in the control group (41 women without ULL), changes in body weight, and in the following indices: Rohrer, Quetelet, Pignet-Verweack, and BMI were analysed. These parameters were evaluated before the intervention and during a 5-year post-operative follow-up.Results: We observed that during the whole period of the control longitudinal study, mean values of body weight and of Rohrer, Quetelet and Pignet-Verweack indices statistically significantly differentiated the group of women with ULL from that without ULL. Only were mean BMI values comparable for both groups of women beginning with the 30th month after the intervention.Conclusions: It was shown that, despite the prolongation of the follow-up period, the anthropometric parameters (aside from the BMI) did not lose their pre-operative significance as factors significantly differentiating the groups of women with and without ULL.
The aim of the study was to determine the impact of the gender of renal allograft donor and recipient on the graft function over a 5-year follow-up period.Material and methods. The 154 kidney grafts from 77 donors transplanted into recipients of both genders. Two study groups were formed: one group consisted of male donors, while the other consisted of female donors. The recipients in each of the groups consisted of a pair, one male and one female.Results. 71% of grafts survived the five-year period in the group of male and female recipients when the donor was male; in case of female donors, the rate was 62.5%. Depending on the gender of the donor and the recipient, the rates of grafts with five-year survival were as follows: 79.2% for male donors and female recipients (MF); 62.5% for male donors and male recipients (MM). The difference between both groups was not statistically significant. In the case of female donors and male recipients (FM), the five-year survival rate was 58.3%, while in female donors and female recipients, the five-year survival rate was 64.1%.Conclusions. Grafts from male donors show a trend towards better five-year survival compared to grafts from female donors. The highest five-year survival rate was observed when the donor was male and the recipient was female; the lowest rate was observed for female donors and male recipients.
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