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Comparison of Iron Oxide-Related MRI Artifacts in Healthy and Neuropathological Human Brain Tissue

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Masarova M., Krafcik A., Teplan M., Strbak O., Gogola D., Boruta P., Dobrota D., Frollo I.
Acta Physica Polonica A
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2017
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vol. 131
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issue 4
1108-1110
EN
The aim of this study is to clarify whether clinical magnetic resonance imaging data can be utilised to evaluate the pathological processes associated with disrupted iron homeostasis, such as neurodegenerative processes or cirrhosis. Although MRI has the potential to become a non-invasive biomarker of such pathology, new quantification methods must be introduced. Our findings confirmed that it is possible to detect significant difference between healthy and pathological tissue from standard T2 weighted MRI protocols.
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