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THE USE OF CHITIN AND CHITOSAN IN MANUFACTURING DRESSING MATERIALS

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Latańska I., Kolesińska B., Draczyński Z., Sujka W.

Progress on Chemistry and Application of Chitin and its Derivatives

2020

vol. 25

16 - 36

Despite continuous progress in the development of advanced dressing materials, there is a constant need for dressings used in an environment of infected and hard-to-heal wounds. Dressings that meet the above described requirements are products based on chitin and its derivatives. Chitosan and chitin derivative dressings are now becoming a very effective medical device in healing hard-to-heal wounds, as well as in the control of severely bleeding wounds. Chitosan and chitin are particularly valuable raw materials that accelerate wound healing processes, and they are also biocompatible and antibacterial. Dressings made of butyric-acetic chitin copolyester are intended for treating wounds of various aetiologies, including chronic wounds in which the healing process is disturbed by concomitant diseases. Materials based on chitosan are also widely used in the area of heavily bleeding and chronic wounds.

Novel side reactions accompanying activation and aminolysis of N-benzoyl-2-alkylserines.

100%

Kamiński Z. J., Woszczyna A., Kolesińska B., Redliński A.

2001

vol. 48

issue 4

1175-1178

2-Phenyl-4-alkyl-4-hydroxymethyl-1,3-oxazolones (2a-d) have been identified as side products accompanying activation of N-benzoyl-2-alkylserines (1a-d). Oxazolones 2a-d in the presence of amine rearrange subsequently to corresponding 4-alkyl-2-phenyl-4,5-dihydro-1,3-oxazole-5 carboxylic acids (4a-d) at a 20-68% yield.

1,3-OXAZOLIDIN-5-ONES DERIVED FROM PROLINE AS CHIRAL COMPONENTS IN THE SYNTHESIS OF PREDICTIVE ENANTIOSELECTIVE COUPLING REAGENTS

88%

Kasperowicz-Frankowska K., Kolesińska B., Gzik A., Jastrząbek K., Kaminski Z. J.

Acta Poloniae Pharmaceutica - Drug Research

2018

vol. 75

issue 4

921-927

1,3-Oxazolidin-5-ones derived from both enantiomers of proline and trichloroacetaldehyde were prepared and applied as amine component in the synthesis of chiral predictive triazine based coupling reagents. The usefulness of these reagents in the condensations yielding enantiomerically enriched products from racemic substrates was presented.

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1 Acta Biochimica Polonica

1 Acta Poloniae Pharmaceutica - Drug Research

1 Progress on Chemistry and Application of Chitin and its Derivatives

1 2020

1 2018

1 2001

3 Kolesińska B.

1 Draczyński Z.

1 Gzik A.

1 Jastrząbek K.

1 Kaminski Z. J.

1 Kamiński Z. J.

1 Kasperowicz-Frankowska K.

1 Latańska I.

1 Redliński A.

1 Sujka W.

1 Woszczyna A.

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THE USE OF CHITIN AND CHITOSAN IN MANUFACTURING DRESSING MATERIALS

Novel side reactions accompanying activation and aminolysis of N-benzoyl-2-alkylserines.

1,3-OXAZOLIDIN-5-ONES DERIVED FROM PROLINE AS CHIRAL COMPONENTS IN THE SYNTHESIS OF PREDICTIVE ENANTIOSELECTIVE COUPLING REAGENTS