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Cytokine profiles of dendritic cells (DCs) during infection with bovine leukaemia virus (BLV)

100%
Iwan E., Szczotka M., Kocki J.
Polish Journal of Veterinary Sciences
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2017
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issue 2
2

The induction of bcl-2 gene expression in human lymphocytes in vitro

99%
Kocki J., Rozynkowa D.
Genetica Polonica
|
1994
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vol. 35
|
issue 1-2
115-125
3
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Determination of cytokine profiles in populations of dendritic cells from cattle infected with bovine leukaemia virus

89%
Iwan E., Szczotka M., Kocki J., Pluta A., Iwan E., Szczotka M., Kocki J., Pluta A.
Polish Journal of Veterinary Sciences
|
2018
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vol. 21
|
issue 4
4
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Determination of telomere length and telomerase activity in cattle infected with bovine leukaemia virus (BLV)

89%
Szczotka M., Kocki J., Iwan E., Pluta A., Szczotka M., Kocki J., Iwan E., Pluta A.
Polish Journal of Veterinary Sciences
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2019
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issue 2
5

Molecular diagnostics of promyelocytic leukaemia

76%
Kocki J., Constantinou M., Cioch M., Lancut M., Kaluzewski B., Dmoszynska A., Wojcierowski J.
Journal of Applied Genetics
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2003
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vol. 44
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issue 4
553-556
EN
Acute promyelocytic leukaemia (APL) is characterised by proliferation of abnormal promyelocytes. The reciprocal translocation between the long arms of chromosomes 15 and 17, and the fusion between the retinoic acid receptor (RARa) gene, and PML gene, is unique to APL. Because of unsuccessful cytogenetic analysis of conventional G-banding technique (mitoses were not observed), we diagnosed three non-treatment patients with APL by following molecular methods: reverse transcription ? polymerase chain reaction (RT-PCR), fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH). At the time of diagnosis our patients showed reciprocal translocation t(15;17)(q22;q12) in all cases studied (66-85% of positive bone marrow cells). With the use of CGH we observed the unbalanced chromosomal aberrations: losses of 5q13.1, 5q31.3, 9p21 regions, gain of 5q32 region and trisomy of 18 chromosome.
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