Backgorund Decreased affective efficiency, preceded by emotional problems, is a common advanced-age disorder which can lead to depression. Aim The aim of this study was to assess the relationship between depressive symptoms experienced by elderly people and their sociodemographic data, self-reported health status, physical fitness, functional capacity, and history of falls. Material and methods The study involved 304 individuals aged 65-100 years. The research instruments were the Geriatric Depression Scale-Short Form, the Barthel Scale, and the Background Survey Geriatric Questionnaire. Results Depression was more common among the elders who had a lower education level, lived alone, were in a worse financial position, and among those whose families were unprepared to provide them with informal care (p < 0.05). Conclusions Depressive symptoms observed in the respondents were significantly related to their sociodemographic data, reduced ability to perform daily activities, low self-reported health status and physical fitness, and recurrent falls.
Background. During the last few decades, adiposity has become a relatively common phenomenon worldwide. The available data on the effects of pro-inflammatory factors in both depression and adiposity has been attracting great attention. Aim. We sought to assess the prevalence of -889C>T IL-1α, -31T>C and -511C>T IL-1β, -330T>G IL-2 and -174G>C IL-6 genes and their association with adiposity and depression in Polish subjects. Methods. A cohort study was conducted in 2013/2014, covering a sample of 297 individuals (217 female and 80 male). Anthropometric data was handled using the BIA analysis method, while for genotyping PCR-RFLP techniques were used. Results. A positive correlation between depression and anthropometric parameters: adipose tissue (in kg) and adipose tissue (in %) (R=0.135 and p=0.02, R=0.114 and p<0.05, respectively) was found. No association between studied polymorphisms and depression was observed. Conclusion. Although it was not possible to demonstrate any influence of the studied polymorphisms as the genetic modulator of depression, authors believe that the presented data are noticeable and may provide the basis for future studies on larger groups.
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