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Trangenic technology as it applies to animal agriculture

100%

Kopchick J., Jura J., Mukerji P., Kelder B.

Biotechnologia

1996

issue 2

31-51

A variety of recombinant DNA molecules have been introduced into the germ line of animals.The results transgenic animals have a diverse range of phenotypes, some of which were expected and some not anticipated.To data, the majority of transgenic animals are mice.However recombinant DNA has been introduced into agriculturally important animals such a sheep, rabbits, pigs, chickens, cattle and fish.In this report, we will survey the consequences of transgene expression in agriculturally important mammals in terms of their effects on growth.Also, we will review the data concerning the use of transgenic mammals as "bioreactors" for the production of recombinant proteins.

Performance of transgenic pigs produced with the use of two different growth hormone gene constructs

64%

Rozycki M., Smorag Z., Kopchick J., Chen W. Y., Jura J., Pasieka J., Orzechowska B., Gajda B., Skrzyszowska M.

Journal of Applied Genetics

1999

vol. 40

issue 1

29-37

Four transgenic pigs, produced with the use of two different gene constructs containing the bovine growth hormone coding gene - Mt-bGH-10D6 (wild type) and Mt-bGH-M8 (mutated), were used to produce the F1 generation to investigate their performance traits. No differences were observed in fattening and slaughter traits between transgenic and non-transgenic pigs. It was found that the weight of ham proper and loin eye area was significantly higher in carriers of Mt-bGH-10D6 gene constructs.

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1 Biotechnologia

1 Journal of Applied Genetics

1 1999

1 1996

2 Jura J.

2 Kopchick J.

1 Chen W. Y.

1 Gajda B.

1 Kelder B.

1 Mukerji P.

1 Orzechowska B.

1 Pasieka J.

1 Rozycki M.

1 Skrzyszowska M.

1 Smorag Z.

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Trangenic technology as it applies to animal agriculture

Performance of transgenic pigs produced with the use of two different growth hormone gene constructs