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Safety of oral nifuroxazide – analysis of data from a spontaneous reporting system

100%
Karlowicz-Bodalska K., Głowacka K., Boszkiewicz K., Han S., Wiela-Hojeńska A.
Acta Poloniae Pharmaceutica - Drug Research
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2019
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vol. 76
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issue 4
745-751
EN
Nifuroxazide is a popular chemotherapeutic agent, that is widely used in Poland in acute and chronic bacterial diarrhea treatment. It is available in pharmacies as over-the-counter tablets for adults and a suspension on prescription for children. The aim of the study was to assess the safety of nifuroxazide therapy. Adverse reaction reports from the Regional Pharmacovigilance Center in Wroclaw, the pharmaceutical company PPF Hasco-Lek, and VigiAccess and EudraVigilance databases were analyzed. Based on the analysis of the data collected from the above sources, nifuroxazide have shown a high therapeutic value in the gastrointestinal tract infections, maintaining high safety of usage at the same time. The number of drug application adverse reactions in Poland is not so high primarily due to high safety profile and low patient awareness of the possibility of reporting drug side effects.
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Farmacja kliniczna - na jakim etapie jesteśmy w Polsce?

86%
Bryla A., Urbańczyk K., Stachowiak A., Burkacka M., Steczko M., Wiela-Hojeńska A.
Farmacja Polska
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2020
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vol. 76
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issue 3
175-182
EN
The functioning of health care centers is highly dependent on the quality of cooperation between medical staff - doctors, nurses, but also pharmacists. Pharmaceutical knowledge about medicines, combined with daily practice and supervision of the pharmacotherapy used, can bring a number of benefits, primarily increasing effectiveness and safety of treatment, as well as reducing the cost of treatment. Despite numerous difficulties, in some hospitals in Poland pharmacists undertake various types of clinical activities by directly joining the work of a hospital ward or remote monitoring of patient's pharmacotherapy using electronic systems. It should be emphasized that these are often tasks carried out outside the basic dimension of working time. The initiative taken in 2017 by the Director of the Provincial Specialist Hospital in Wroclaw, Research and Development Center, deserves a mention. Pharmacist (during the specialization in clinical pharmacy) was fully engaged in the work of hospital wards focusing first in the Department of Vascular Surgery, and then also General Surgery. Her daily duties include participation in medical celebrations, conducting medical history with newly admitted patients, optimization of pharmacotherapy, consultation with the medical and nursing team, control of orders and results of laboratory tests, giving advice to staff and educating patients in correct use of medicines. This kind of multidisciplinary cooperation has become a standard of care, which has been approved by the accreditation committee of the Center for Quality Monitoring in Health Care. In Poland, clinical pharmacy is constantly developing and gaining importance every year, but as of today, there are still no clear law regulations. Will the draft Act On The Pharmacy Profession adopted by the Council of Ministers introduce regulations and clearly define the place of a clinical pharmacist in the healthcare system? Undoubtedly, it would be a basic step to the further development of clinical pharmacy services.
PL
Funkcjonowanie placówek ochrony zdrowia w dużym stopniu zależne jest od jakości współpracy między personelem medycznym – lekarzami, pielęgniarkami, ale także farmaceutami. Wiedza farmaceutyczna na temat leków, połączona z codzienną praktyką i sprawowowanie nadzoru nad stosowaną farmakoterapią, może przynieść szereg korzyści, przede wszystkim zwiększenie skuteczności i bezpieczeństwa leczenia, a także obniżenie jego kosztów. W Polsce obserwuje się rozwój farmacji klinicznej, jednak jego tempo jest wolne, gdyż stale brak jest jednoznacznych umocowań prawnych do zatrudniania farmaceutów klinicznych. Czy przyjęty przez Radę Ministrów, projekt Ustawy o zawodzie farmaceuty wprowadzi takie możliwości i wyraźnie określi miejsce farmaceuty klinicznego w systemie opieki zdrowotnej? Bez wątpienia byłby to podstawowy krok do dalszego rozwoju usług farmacji klinicznej.
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