Search results

1

The contribution of AT1 and AT2 angiotensin receptors to its cognitive effects

100%

Braszko J.

Acta Neurobiologiae Experimentalis

|

1996

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vol. 56

|

issue 1

49-554

EN

In this study I attempted to assess, in rats, the role of AT(1) and AT(2) angiotensin receptor subtypes in the phenomenon of improved learning and memory after an intracerebroventricular (icv) injection of angiotensin II (Ang II) and Ang II (3-7). Selective AT(1) (losartan, 1mg) or AT(2) (CGP 42112 A, 2 mugg) receptor antagonist was dissolved in 2 mugl of saline and given to the left cerebral ventricle 5 min before 1nmol Ang II or Ang II (3-7) injected in the same volume of saline to the right ventricle. Consequently, there were 9 experimental groups which underwent 3 memory oriented and 3 auxiliary tests. Ang II and Ang II (3-7) significantly improved retention of passive avoidance and recognition memory. These effects were abolished by losartan or CPG 42112 A.Better, after Ang II And Ang II (3-7), acquisition of conditioned avoidance responses was unchanged by losartan and abolished by CGP 42112 A. None of the treatments significantly changed rats motor behaviour in open field. Losartan as well as CGP 42112 A abolished significant enhancement of apomorphine (1 mg/kg, ip) stereotypy caused by Ang II and Ang II (3-7). The results suggest considerable involvement of AT(1) and AT(2) angiotensin receptors in the cognitive enhancement produced by angiotensins.

2

The widespread but silent cerebral mineralization: a case report

100%

Kuchna I., Laure-Kamionowska M., Walkiewicz W.

Acta Neurobiologiae Experimentalis

|

1993

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vol. 53

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issue 1

285-288

EN

We present a sporadic infantile case of primary cerebral mineralization with unexpected asymptomatic clinical course. An 11 months old boy with negative familial and gestational data developed normally. He died after two days of fever and rapid course of cardiorespiratory failure due to pneumonia. Parathyroid dysfunction and somatic abnormalities were not evident clinically. Neuropathological examination revealed bilateral, diffuse or pericapillary calcifications in the striatum, cerebral and cerebellar cortex, dentate nucleus and brain stem. The mineralizations were less prominent in the cerebral hemispheres than in cerebellum. A diffuse demyelination was seen in the cerebellum where calcifications were numerous. We suggest that the intracerebral calcifications progressed gradually through a disease course and probably started in the cerebellum. We discuss the lack of clinico-pathological correlations and the nosologic position of the observed syndrome.

3

Frequency of occurrence of species of the Paramecium aurelia complex in Europe

100%

Przybos E.

Folia Biologica

|

1998

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vol. 46

83-86

EN

The scattered in the literature data on the occurrence and distribution of the Paramecium aurelia spp. complex in Europe are compiled in the present communication. The number of investigated clones and habitats as well as the ratio value (r.v.), i.e. the number of habitats for a defined species to the total number of habitats of the area were taken into consideration when the frequency of species occurrence was estimated. Among 8 species present in Europe, P. novaurelia is a dominant species (r.v. 0.45), P. biaurelia is a frequent one (r.v. 0.37), and P. primaurelia less frequent (r.v. 0.27). Other species are rare, i.e. P. tredecaurelia, P. pentaurelia, P. sexaurelia, P. triaurelia, and P. tetraurelia.

4

Effect of early illumination conditions on illumination preferences in the ant

100%

Korczynska J., Godzinska E. J.

Acta Neurobiologiae Experimentalis

|

1995

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vol. 55

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issue 3

222

5

Bacterial ion channels

100%

Kubalski A., Koprowski P.

Postępy Higieny i Medycyny Doświadczalnej

|

2000

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vol. 54

|

issue 3

317-327

EN

After an overview of potassium and chloride ion channels found in bacterial inner membrane this review focuses on mechanosensitive ion channels from the inner membrane of Escherichia coli. Mechanosensitive channels, MscL and MscS, have major roles in managing the transition from high to low environments. Biochemical and genetic studies of MscL, combined with structural information derived from X-ray crystalography, have brought the knowledge of how a mechanosensitive channel senses membrane tension. Physiological studies on MscL and on MscS have demonstrated how the mechanosensitive channels contribute to the bacterial membrane response upon hypo-osmotic stress.

6

Spontaneous spike-wave discharges in rat neocortex and their relation to behaviour

100%

Gralewicz S., Wiaderna D., Stetkiewicz J., Tomas T.

Acta Neurobiologiae Experimentalis

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2000

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vol. 60

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issue 3

323-332

EN

A certain proportion of laboratory rats of various strains show spontaneous nonconvulsive ECoG seizures in the form of bursts of spike-and-wave discharges (SWD). Since in the majority of behavioural experiments the EEG is not controlled, the experimenter is usually unaware of this fact. The purpose of the present work was to find out whether the SWD trait is related to the rats behavioural performance in selected test situations. The experiment was performed on two groups of male Wistar rats, outbreds, aged six (group 6M, n = 17) and 24 months (group 24M, n = 14). First, in both groups the following forms of behaviour were assessed: (1) seeking water reward in an 8-arm radial maze, (2) exploration of a new object, (3) inhibition of a locomotor response (passive avoidance), and (4) paw-lick response to a thermal stimulus (54.5oC) applied to the feet before and after intermittent footshock. The rats were then implanted with intrabrain electrodes and the level of SWD activity was assessed. Rats of the 24M group, compared with those of the 6M one, showed a significantly shorter exploratory response to a new object and diminished responsiveness to heat. The groups did not differ, however, in passive avoidance and radial maze performance. The analysis of 3-h ECoG sections revealed SWD bursts in 73% and nearly 93% of rats from groups 6M and 24M, respectively. The groups did not differ in the number of bursts or in the total duration of SWD activity. A correlation analysis of pooled data from both groups revealed that the exploration time of a new object was significantly (negatively) correlated with the number of SWD episodes. The total duration of SWD activity, and the number of perseveration errors in the radial maze, was significantly (positively) correlated with the total duration of SWD activity. The results suggest that SWD rats are behaviourally impaired in some test situations.

7

Quantitative measure of complexity of EEG signal dynamics

100%

Klonowski W., Jernajczyk W., Niedzielska K., Rydz A., Stepien R.

Acta Neurobiologiae Experimentalis

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1999

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vol. 59

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issue 4

315-321

EN

Since electroencephalographic (EEG) signal may be considered chaotic, Nonlinear Dynamics and Deterministic Chaos Theory may supply effective quantitative descriptors of EEG dynamics and of underlying chaos in the brain. We have used Karhunen-Loeve decomposition of the covariance matrix of the EEG signal to analyse EEG signals of 4 healthy subjects, under drug-free condition and under the influence of Diazepam. We found that what we call KL-complexity of the signal differs profoundly for the signals registered in different EEG channels, from about 5-8 for signals in frontal channels up to 40 and more in occipital ones. But no consistency in the influence of Diazepam administration on KL-complexity is observed. We also estimated the embedding dimension of the EEG signals of the same subjects, which turned to be between 7 and 11, so endorsing the presumption about existence of low-dimensional chaotic attractor. We are sure that nonlinear time series analysis can be used to investigate the dynamics underlying the generation of EEG signal. This approach does not seem practical yet, but deserves further study.

8

Interneuronal cortical connections and intertrial responses in appetitive instrumental learning

100%

Merzahanova G. K.

Acta Neurobiologiae Experimentalis

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1997

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vol. 57

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issue 3

247-253

EN

The organization of interneuronal cortical connections in intertrial periods was studied in 4 cats trained to perform the delayed appetitive instrumental response to a visual conditioned stimulus (CS). Crosscorrelational analysis revealed changes in intra- and intercortical neuronal networks of the visual and motor cortical projection areas. Depending on the form of behavior in the intertrial period, i.e., the presence or absence of the acquired instrumental response, the functional connections of either informational (time delays of less than 30 ms) or motivational (time delays in the range of 60-100 ms) character dominated between the neurons of the motor and visual cortical areas.

9

A prospective study of prenatal mercury exposure from maternal dental amalgams and autism severity

100%

Geier D. A., Kern J. K., Geier M. R.

Acta Neurobiologiae Experimentalis

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2009

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vol. 69

|

issue 2

189-197

EN

Dental amalgams containing 50% mercury (Hg) have been used in dentistry for the last 150 years, and Hg exposure during key developmental periods was associated with autism spectrum disorders (ASDs). This study examined increased Hg exposure from maternal dental amalgams during pregnancy among 100 qualifying participants born between 1990.1999 and diagnosed with DSM-IV autism (severe) or ASD (mild). Logistic regression analysis (age, gender, race, and region of residency adjusted) by quintile of maternal dental amalgams during pregnancy revealed the ratio of autism:ASD (severe:mild) were about 1 (no effect) for .5 amalgams and increased for .6 amalgams. Subjects with .6 amalgams were 3.2-fold significantly more likely to be diagnosed with autism (severe), in comparison to ASD (mild), than subjects with .5 amalgams. Dental amalgam policies should consider Hg exposure in women before and during the child-bearing age and the possibility of subsequent fetal exposure and adverse outcomes.

10

Reduced degree of long-range phase synchrony in pathological human brain

100%

Bhattacharya J.

Acta Neurobiologiae Experimentalis

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2001

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vol. 61

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issue 4

309-318

EN

In this paper multivariate spontaneous EEG signals from three broad groups of human subjects - control, seizure, and mania - were studied with the aim of investigating the possible effect of these pathologies on the degree of phase synchronization between cortical areas. The degree of phase synchrony was measured by two recently developed measures which are more suitable than classical indices like correlation or coherence when dealing with nonlinear and non-stationary signals like the EEG. Signals were reduced to seven frequency bands (delta, theta, alpha-1, alpha-2, beta-1, beta-2 and gamma) which were statistically compared between the normal and the other two groups. It was found that the degree of long-range synchrony was significantly reduced for both pathological groups as compared with the control group. No clear differences were found in the degrees of short-range synchrony.

11

The second layer neurones of the entorhinal cortex and the perforant path in physiological agening and Alzheimer's disease

100%

Morys J., Sadowski M., Barcikowska M., Maciejewska B., Narkiewicz O.

Acta Neurobiologiae Experimentalis

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1994

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vol. 54

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issue 1

47-53

12

Oscillatory cortical activities in the gamma band in the human EEG induced by visual stimuli - representation of the stimulus?

100%

Muller M. M.

Acta Neurobiologiae Experimentalis

|

2000

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vol. 60

|

issue 1

49-65

EN

The present work presents three experiments investigating cortical activities in the gamma band in humans. On the basis of theoretical models and animal experiments, synchronized oscillatory neuronal activity is discussed as the key mechanism by which the brain binds information processesed in different cortical areas to form a percept. Using an identical stimulation design - the same as used in animal studies - it was shown that induced gamma band responses in the EEG resemble the same features as those found in the intracortical recordings of animals. In addition, the present work demonstrates that these cortical activities are not higher harmonics of the alpha band and that they are senstive to the features of the stimulus. These results support the notion that gamma band activity is not just a by-product of neuronal activity and that alpha- and gamma band activies most certainly represent different cortical funtional states.

13

Holocentric chromosomes of Psocids (Insecta, Psocoptera) analysed by C-banding, silver impregnation and sequence specific fluorochromes CMA3 and DAPI

100%

Golub N. V., Nokkala S., Kuznetsova V. G.

Folia Biologica

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2004

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vol. 52

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issue 3-4

143-149

EN

The pattern of nucleolus attachment and C-heterochromatin distribution and molecular composition in the karyotypes of psocid species Psococerastis gibbosa (2n = 16+X), Blaste conspurcata (2n = 16+X) and Amphipsocus japonicus (2n = 14+neo-XY) were studied by C-banding, silver impregnation and sequence specific fluorochromes CMA3 and DAPI. Every species was found to have a single nucleolus in male meiosis. In P. gibbosa the nucleolus is attached to an autosomal bivalent; in B. conspurcata to the X-chromosome; in A. japonicus to the neo-XY bivalent. The species show a rather small amount of constitutive heterochromatin, C-blocks demonstrating telomeric localization with rare exceptions. P. gibbosa is characterized by a polymorphism for C-blocks occurrence and distribution. In the autosomes of this species, C-heterochromatin consists of AT-rich DNA except for the nucleolus organizing region, which is also GC-rich; the X-chromosome shows both AT- and GC-rich clusters. In A. japonicus and B. conspurcata, C-heterochromatin of the autosomes and sex chromosomes consists of both GC-rich and AT-rich DNA clusters, which are largely co-localized.

14

Development of the tongue and taste disks in Pelobates fuscus

100%

Zuwala K.

Folia Biologica

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2002

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vol. 50

|

issue 3-4

165-172

EN

In the tadpole of Pelobates fuscus the process of tongue formation starts at the 32nd developmental stage. In more advanced stages (older than 38th) fast anterior and faucial growth of the tongue fold has been observed. This process is accompanied by the development of the gustatory organs. The dorsal surface of the tongue fold, smooth at the beginning, in older tadpoles (developmental stages 36-39th) forms protrusions in which gustatory organs of the taste disk type (TDs) develop. In the 41st tadpole developmental stage anlages of TDs are formed by elongated cells, located more or less perpendicularly to the surface of the tongue. The diameter of the sensory area of a TD at the 45th developmental stage amounts to 94 ?m, while in metamorphosed individuals it reaches 130-140 ?m. At the base of a TD the presence of basal cell morphologically similar to that of Merkel cell was observed at the 42nd developmental stage of a tadpole. Fully developed afferent synaptic connections in the sensory epithelium of a TDwere found starting from the 44th developmental stage. Single synaptic vesicles with an electron-dense core were observed in gustatory cells as early as at the 41st developmental stage of the tadpole. From the observations reported here it can be inferred that in Pelobates fuscus development of both the tongue and TDs is similar to that already described in the representatives of the Rana genus.

15

Progress in diagnosis of Heliobacter pyroli infection

100%

Chmiela M., Lawnik M.

Postępy Higieny i Medycyny Doświadczalnej

|

1997

|

vol. 51

|

issue 1

75-93

EN

A wide range of techniques was developed for identification of Helicobacter pylori, since the association of the microorganism with gastritis and peptic ulcer has been established in 1983. Up to now, isolation and identification of H. pylori from the gastric biopsy, remains the standard diagnostic procedure. However, attention is focused on rapid no-invasive tests, for monitoring the infection, such as urea breath test. Serological methods as ELISA and Western blot are suitable for estimation of specific anti - H. pylori local and systemic humoral response. Molecular tests based on PCR reaction allow the detection of H. pylori in biopsy specimens and recently in other clinical samples as saliva or faeces. They are also very promissing in epidemiological studies.

16

Carotenoid content in Lota lota (L.) individuals in various biological activity periods

100%

Czeczuga B., Czeczuga-Semeniuk E.

Folia Biologica

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1999

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vol. 47

|

issue 3-4

67-72

EN

The authors investigated the carotenoid content in the particular parts of Lota lota in summer, autumn, and winter, i.e. when burbots exhibit the lowest and highest activity. By means of columnar and thin-layer chromatography, the following carotenoids were found to be presenct: a-carotene, b-carotene, e-carotene, b-cryptoxanthin, neothxanthin, lutein, 3?-epi- lutein, zeaxanthin, tunaxanthin, antheraxanthin, lutein epoxide, echinenone, 3?-hydroxy- echinenone, idoxanthin, canthaxanthin, a-doradexanthin, b-doradexanthin, astaxanthin, diatoxanthin, parasiloxanthin, monadoxanthin, 7,8-dihydroparasiloxanthin, mutatoxanthin and rhodoxanthin. In the Lota lota individuals examined, the content of carotenoids was found to differ in winter and summer. The total carotenoid content ranged from 0.067 (gonads of males) of to 6.095 ?g g-1 wet weight (fins of males from December).

17

Molecular and cellular basis of interactions

100%

Zastawny T. H., Olinski R.

Postępy Higieny i Medycyny Doświadczalnej

|

1993

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vol. 47

|

issue 2

101-121

EN

Cis-DDP is an with activity against various . It is generally accepted that is the of cis-DDP. The present paper describes the binding models of cis-DDP to DNA, structural distortion in DNA induced by covalent binding of cis-DDP and repair studies of Pt-DNA adducts in pro- and eucariotic systems. We also discuss the possible mechanisms of acquired of to cis-DDP and analoques, and potential clinical implication of this fenomenon.

18

Sialic acid containing lipopolysaccharides

100%

Gamian A.

Postępy Higieny i Medycyny Doświadczalnej

|

1996

|

vol. 50

|

issue 5

459-472

EN

Sialic acids which are important constituents of animal tissue glycoconjugates are also present in antigens of some bacterial strains. Capsular polysaccharides with sialic acid have been extensively studied whereas little is known on lipopolysaccharides which contain sialic acid. The paper presents review of the data concerning structure of bacterial endotoxic lipopolysaccharides. Methodological peculiarities were described. Specially emphasized were endotoxins of Escherichia coli O24, O56, O104, Salmonella toucra O48, Citrobacter freundii O37 and Hafnia alvei strain PCM2386.

19

Defined serum-free culturing conditions for neural tissue engineering of human cord blood stem cells

100%

Ali H., Jurga M., Kurgonaite K., Forraz N., McGuckin C.

Acta Neurobiologiae Experimentalis

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2009

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vol. 69

|

issue 1

12-23

EN

Taking tissue engineering applications into clinical trials requires the development of efficient and safe protocols incorporated with effective 3-dimentional cell culturing and differentiation systems in order to develop transplantable tissues that may offer a life-line for patients in the future. Cord blood, which is perhaps the most abundant world stem cell source, has shown previously practical and ethical advantages over other stem cells sources in many research and clinical applications including regenerative medicine. We previously developed a three-step protocol for isolation, expansion and sequential neuronal differentiation of cord blood pluripotent stem cells (characterized with our unique triple immunocytochemisty scheme for Oct-4, Sox-2 and Nanog) in defined serum-free culturing conditions. In this study we incorporated this protocol with 3-dimentional culturing systems which produced artificial neuronal tissues expressing Nestin, NF-200, TUJ1, PSD-95 and NeuN. We showed that cord blood pluripotent stem cells are a potential and promising candidate for future neural tissue engineering and regenerative medicine.

20

Complexity analysis of spontaneous EEG

100%

Bhattacharya J.

Acta Neurobiologiae Experimentalis

|

2000

|

vol. 60

|

issue 4

495-501

EN

The aim of the present paper is the assessment of the overall complexity of spontaneous and non-paroxysmal EEG signals obtained from three groups of human subjects, e.g., healthy, seizure and mania. Linear complexity measure suitable for multi-variate signals, along with nonlinear measures such as approximate entropy (ApEn) and Taken?s estimator are considered. The degree of linear complexity is significantly reduced for the pathological groups compared with healthy group. The nonlinear measures of complexity are significantly decreased in the seizure group for most of the electrodes, whereas a distinct discrimination between the maniac and healthy groups based on these nonlinear measures is not evident.

Refine search results

The contribution of AT1 and AT2 angiotensin receptors to its cognitive effects

The widespread but silent cerebral mineralization: a case report

Frequency of occurrence of species of the Paramecium aurelia complex in Europe

Effect of early illumination conditions on illumination preferences in the ant

Bacterial ion channels

Spontaneous spike-wave discharges in rat neocortex and their relation to behaviour

Quantitative measure of complexity of EEG signal dynamics

Interneuronal cortical connections and intertrial responses in appetitive instrumental learning

A prospective study of prenatal mercury exposure from maternal dental amalgams and autism severity

Reduced degree of long-range phase synchrony in pathological human brain

The second layer neurones of the entorhinal cortex and the perforant path in physiological agening and Alzheimer's disease

Oscillatory cortical activities in the gamma band in the human EEG induced by visual stimuli - representation of the stimulus?

Holocentric chromosomes of Psocids (Insecta, Psocoptera) analysed by C-banding, silver impregnation and sequence specific fluorochromes CMA3 and DAPI

Development of the tongue and taste disks in Pelobates fuscus

Progress in diagnosis of Heliobacter pyroli infection

Carotenoid content in Lota lota (L.) individuals in various biological activity periods

Molecular and cellular basis of interactions

Sialic acid containing lipopolysaccharides

Defined serum-free culturing conditions for neural tissue engineering of human cord blood stem cells

Complexity analysis of spontaneous EEG