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Association of the thickness of carotid intima-media complex and ancle brachial index with coronary disease severity

100%
Kostić S., Tasić I., Mijalković D., Lović D., Djordjević D., Savić T., Tasić N., Aranđelović A.
Open Medicine
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2014
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vol. 9
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issue 5
601-608
2
Content available remote

Health-related quality of life in patients with coronary artery disease after coronary revascularization

100%
Tasić I., Lazarević G., Stojanović M., Kostić S., Rihter M., Djordjević D., Simonović D., Vulić D., Stefanović V.
Open Medicine
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2013
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vol. 8
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issue 5
618-626
EN
The aim of this study was to investigate the quality of life (HRQoL) in coronary artery disease(CAD) patients, admitted for rehabilitation within 3 months after an acute coronary event, in relation to treatment strategy [conservative treatment without revascularization (WR), percutaneous transluminal coronary angioplasty (PTCA), coronary artery bypass graft (CABG)]. Methods: Overall 719 consecutive CAD patients were involved in the study: WR (n=170), PTCA (n=226), CABG (n=323). HRQoL was estimated using the SF-36 questionnaire for total QoL and its two dimensions for physical and mental health [physical and mental component scores (PCS, MCS)]. Sexual dysfunction was assessed using the ASEX scale. Results: Significantly higher PCS, MCS and total SF-36, but lower ASEX score, were found in men compared with women. The ASEX score was significantly affected by age. Significantly higher PCS was found in PTCA group compared with that of CABG group. In multivariate analysis a significant positive association was obtained between PCS/MCS and male sex, between regular exercise, hyperlipoproteinemia, and permanent stress. ASEX was significantly positively associated with the age, CHF and non smoking. Conclusion: The results of this study have demonstrated significantly better HRQoL in men, younger CAD patients, patients who underwent PTCA and in patients without self-reported exposition to stress.
3
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Correlation between total cardiovascular risk and bone density in postmenopausal women

81%
Popovic M., Tasić I., Dimić A., Stojanović S., Stamenković B., Kostić S., Popović D., Savić T., Tasić N., Manojlovic S., Ivanović B.
Open Medicine
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2011
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vol. 6
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issue 6
795-803
EN
The aim of the paper was to examine the correlation between the total risk of cardiovascular events, determined by the SCORE (Systematic Coronary Risk Evaluation) system, and bone density in postmenopausal women. Examinees and method: The research involved 300 postmenopausal women. On the basis of bone density measurements, the participants were divided into three groups: group I - 84 examinees had osteoporosis, group II - 115 examinees had osteopenia, and group III - 101 examinees had normal bone mineral density (BMD). Results: Participants with high SCORE risk were statistically significantly older compared to low-risk women (60±3 vs. 55±5; p<0.001). They had significantly lower BMD and T scores (−1.09±0.94 vs. −2.86±0.63; p<0.001). Elevation of the SCORE risk by 1% caused a BMD decrease of 0.033 g/cm2(0.029 to 0.036 gr/cm2). Multivariate logistic regression analysis showed that the following factors caused a significant increase in the risk of decreasing BMD: every year of life by 20%, menopause duration by 26%, increase in systolic blood pressure (BP) by 1 mm Hg by 7%, increase in SCORE risk by 1% by 5.31 times, physical inactivity by 5.96 times, and osteoporosis in the family history by 3.91 times. Conclusion: Postmenopausal women who are at high risk for cardiovascular diseases have a lower BMD than those who are not at high risk for cardiovascular diseases.
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