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Pseudarthrosis in fibrous dysplasia treated with bone morphogenetic protein

100%

Beckmann J., Kock F., Tingart M., Goetz J., Grifka J., Schaumburger J.

Open Medicine

2008

vol. 3

issue 3

377-379

We present a case of pseudarthrosis in a patient suffering from polyostotic fibrous dysplasia of the right part of the body that was successfully treated with bone morphogenetic protein. Pseudarthrosis occurred after proximal femoral shaft fracture due to a motorcycle accident initially treated by intramedullary nailing. After revision, the patient was treated by pseudarthrosis debridement and grafting of bone morphogenetic protein-7/osteogenic protein-1, resulting in callus formation that allowed indolent full weight-bearing after 6 weeks. The underlying disease as well as the described treatment is discussed.

Regulation of gene expression in articular cells is influenced by biomechanical loading

84%

Rath B., Springorum H.-R., Deschner J., Lüring C., Tingart M., Grifka J., Schaumburger J., Grässel S.

Open Medicine

2012

vol. 7

issue 4

545-552

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2 Open Medicine

1 2012

1 2008

2 Grifka J.

2 Schaumburger J.

2 Tingart M.

1 Beckmann J.

1 Deschner J.

1 Goetz J.

1 Grässel S.

1 Kock F.

1 Lüring C.

1 Rath B.

1 Springorum H.-R.

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Pseudarthrosis in fibrous dysplasia treated with bone morphogenetic protein

Regulation of gene expression in articular cells is influenced by biomechanical loading