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The future of internal medicine in the United States and Poland

100%
Wilson C. M., Taylor O., Prystupa A., Załuska W.
Polish Journal of Public Health
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2015
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vol. 124
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issue 1
49-54
EN
Internal medicine physicians are critical to the health of the population. Internal medicine doctors also bring cost savings in health care because they treat many systems in the body and treat the patients in a holistic manner. However, the popularity of the specialty of internal medicine is declining. This is due to the decreased compensation that internal medicine doctors obtain when compared to their colleagues who specialize in other fields. The decline in number of physicians specializing in internal medicine causes a decrease in the health of the population. Governments and policy makers must look for ways to reverse the trend of doctors not specializing in internal medicine
2
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Different faces of a febrile state

100%
Rymarz E., Milaniuk S., Prystupa A., Mosiewicz J.
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vol. 27
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issue 2
111-112
EN
Fever develops in various diseases. It is mainly associated with infectious diseases but can also occur in non-infectious ailments. Clinical symptoms are not always explicit, which can hinder the diagnosis and delay the institution of appropriate treatment. The aim of the study is to present difficulties in diagnosing the cause of a febrile state in a patient with splenic abscess.
3
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Association between concentration of melatonin, and lipoproteins, LPO, hsCRP, NTproBNP in chronic heart failure patients

64%
Kimak E., Dzida G., Duma D., Prystupa A., Halabis M., Kimak A., Zieba B., Kaznowska-Bystryk I., Kowalska A.
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vol. 27
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issue 3
159-164
EN
The aim of the study was to examine concentrations and relationships between melatonin levels assessed at 0:200 hrs and 0:700 hrs, lipid hydroperoxide (LPO) assessed at 0:200 hrs and 0:700 hrs, and apolipoprotein (apo)AI, apoAII, apoB, high sensitivity C-reactive protein (hsCRP) and NT-proBNP, in 27 patients with chronic heart failure (CHF) (17 patients - with NYHA class II and 10 - with NYHA class III). In the study, Lipoproteins apoAI, apoAII, apoB, high sensitivity C-reactive protein (hsCRP) levels were determined by way of immunonephelometric methods, serum melatonin concentration was measured by using a competitive enzyme immunoassay technique, while serum LPO concentration was measured by using Cayman’s Lipid Hydroperoxide Assay Kit. In the study, CHF patients without acute inflammatory response demonstrated a decreased concentration of high density lipoprotein cholesterol (HDL-C), apoAI, apoAII levels, but an increased concentration of NT-proBNP, hsCRP and LPO at night, and LPO at daytime; however, the concentration of LPO at 0:700 was lower than at 0:200. Pearson’s correlation test and multiple ridge stepwise regression showed that melatonin administered at night exerts an effect on the composition of apoAI and apoAII of HDL particles, and induces decreased LPO at 0:700, but has no effect upon NT-proBNP levels in patients with NYHA class II. However, in patients with NYHA class III, melatonin administered at night induces an increase in the content of apoAII and apoAI, which further decreases hsCRP, and this, together with the administered melatonin, brings about daytime decreases in NT-proBNP and hsCRP levels. The results indicated that the content of apoAII and apoAI in HDL particles and melatonin demonstrate an anti-oxidative and anti-inflammatory effect, and together, have a cardio-protective effect on patients with advanced CHF. Hence, the results support melatonin being a cardio-protective agent. These relationships, however, need to be confirmed in further studies.
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