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Synthesis and spectral analysis of (E)-1-(2,4-dihydroxy phenyl)-3-(4-hydroxyphenyl) prop-2-en-1-one

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Chopda J. V., Patel J. P., Parsania P. H.
World News of Natural Sciences
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2023
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vol. 46
46-52
EN
Multifunction chalcone: (E)-1-(2,4-dihydroxy phenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one (THCH) was synthesized by reacting a 0.01 mol 2,4-dihydroxy acetophenone, and a 0.01 mol 4-hydroxybenzaldehyde using 10 ml of 60% aq. sodium hydroxide as a catalyst and 25 ml of ethanol as a solvent at reflux temperature for 3h. The THCH was crystallized using a water-methanol system. The structure of THCH was supported by UV-Vis, FTIR, 1HNMR, 13CNMR, and mass spectroscopic techniques.
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