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PHYSICAL EXERCISES FOR PRE-SCHOOL CHILDREN WITH HOMEWORK AND PARENTS MOBILIZATION AROUND THESE TASKS

100%

Piech K., Nowak K., Birontiene Z., Bula-Biteniece I.

Polish Journal of Sport and Tourism

2013

vol. 20

issue 3

217-221

Introduction. Results presented in this article are part of an international project called Project of physical activity stimulation in a family (PPASF) held jointly with the Klaipėda University and LASE in Riga. We decided to check whether participation of children in preschool age in active classes in nursery school may be an impetus to change behavior in terms of physical activity of a family. For this purpose, a model was developed that included physical activity program conducted in the nursery school, with homework for the children to do together with their parents at home. The aim of the study was to examine the extent to which a child can persuade the parents to a common physical activity and whether sport and recreation for children with homework are a successful proposal to increase motor activity of the family. Material and methods. A diagnostic survey method was applied in the research, using a questionnaire technique. The survey questionnaire covered 38 families including 30 mothers and 8 fathers. Results and conclusions. Research has shown that children can become facilitators of physical activity in the family. The proposed model classes for children proved to be an accurate proposal, which is worth to implement the practice of teaching.

Badanie wpływu Selolu na ekspresję genów kodujących transportery błonowe i enzymy metabolizujące leki w komórkach nowotworowych wrażliwych i opornych

88%

Dudkiewicz Wilczyńska J., Grabowska A., Książek I., Nowak K., Anuszewska E.

Annales Academiae Medicae Silesiensis

2011

vol. 65

issue 5-6

7-13

The objective of this study was to demonstrate diff erences in the gene expression of human cervical cancer cells (HeLa) and vinblastine-resistant KB-V1 subline treated with doxorubicin alone and combination of Selol 5% and doxorubicin. Ongoing studies seek to clarify the mechanism of action of Selol in diff erent types of cancer cells, including those which show multidrug resistance. Cells treatment with the tested compounds in the group of genes tested in HeLa cells causes other changes than in KB-V1 cells. In the resistant cells, exposure to Selol 5% and doxorubicin, released the cytotoxic eff ects by changing the expression of ABCC2 and BCL2L1 genes. The observed dependence also allows better understanding the molecular mechanisms of resistance in the KB-V1 cell line.

Celem pracy było wykazanie różnic w ekspresji genów komórek ludzkiego nowotworu szyjki macicy (HeLa) i opornej na winblastynę podlinii KB-V1, poddanych działaniu samej doksorubicyny oraz po łącznym podaniu Selolu 5% i doksorubicy. Prowadzone badania zmierzają do wyjaśnienia mechanizmu działania Selolu w różnych typach komórek nowotworowych, w tym opornych wielolekowo. Poddanie komórek działaniu testowanych związków powoduje inne zmiany w grupie badanych genów w komórkach HeLa niż w komórkach KB-V1. Łączne podanie Selolu 5% i doksorubicyny wyzwala efekt cytotoksyczny w komórkach opornych KB-V1, co przypuszczalnie jest związane ze zmianą ekspresji genów ABCC2 i BCL2L1. Zaobserwowana zależność pozwala także lepiej zrozumieć molekularne podłoże oporności komórek linii KB-V1.

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1 Annales Academiae Medicae Silesiensis

1 Polish Journal of Sport and Tourism

1 2013

1 2011

2 Nowak K.

1 Anuszewska E.

1 Birontiene Z.

1 Bula-Biteniece I.

1 Dudkiewicz Wilczyńska J.

1 Grabowska A.

1 Książek I.

1 Piech K.

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PHYSICAL EXERCISES FOR PRE-SCHOOL CHILDREN WITH HOMEWORK AND PARENTS MOBILIZATION AROUND THESE TASKS

Badanie wpływu Selolu na ekspresję genów kodujących transportery błonowe i enzymy metabolizujące leki w komórkach nowotworowych wrażliwych i opornych