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The Distribution of Biological Particles Suspended in Normal Cerebrospinal Fluid (CSF)

100%
Staroń W., Herbowski L.
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issue 1
159-160
EN
Cerebrospinal fluid's functions are protecting, expelling and transporting which are influenced by properties of the fluid. Disorder of one of the functions may bring a disease. Cerebrospinal fluid mainly consists of water (99%), cells and proteins suspended in it. Due to the suspension it can be considered as dispersion medium. Every dispersion medium is characterized by the parameters of particles suspended in it. Parameters of dispersion medium may be classified as single or cumulative parameters. Hence, there is possible to determine additional parameters which characterize CSF in order to give full description of the fluid. The authors present results of research on suspension in normal cerebrospinal fluid worked out on the basis of 2500 microscoping pictures and they also give a statistical analysis of particle diameters. The paper is a part of research project on "Physico-chemical processes in cerebrospinal fluid obtained by puncture from patients diagnosed with the disorders of cerebrospinal fluid (CSF) circulation" realized by Institute of Physics, University of Szczecin in co-operation with Neurosurgery Ward of Public Provincial Hospital Complex in Szczecin.
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Preliminary Analysis of Size Distribution of Objects Suspended in Normal Cerebrospinal Fluid in Case of Venticular Hydrocephalic Enlargement and Internal Hydrocephalus

81%
Staroń W., Kubisz L., Herbowski L.
Acta Physica Polonica A
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2012
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vol. 121
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issue 1A
A-46-A-48
EN
The paper presents preliminary analysis of normal non-coloured cerebrospinal fluid obtained from patients diagnosed due to suspicion of cerebrospinal fluid malabsorption. According to the findings, the normal cerebrospinal fluid was classified into two groups: A - with clinical diagnosis of ventricular hydrocephalic enlargement and B - with clinical diagnosis of internal hydrocephalus. The analysis of microscopic pictures of normal cerebrospinal fluid in both groups according to numbers and sizes of suspended objects was performed with the aid of Eclipse 600 microscope (with magnification of 1200×) working with a computer by a digital video camera. The authors observed that there is a significant difference in a shape of the distribution curve of objects' diameters between groups A and B. The maximum number of objects in group A was recorded within the range from 5 to 10 μm in diameter size whereas in group B the maximum was recorded within the range from 0.5 to 5 μm in diameter size.
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