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EN
In the review some concepts of molecular mechanisms of nephrotoxic and ototoxic action of aminoglycosides was presented. They way to changes of aminoglycoside administration frequency, and reduction of side-effects was discussed.
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1996
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vol. 50
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issue 6
621-633
EN
In the paper there were described some problems concerning influence of aluminium on central nervous system mainly. It was shown some aspects of neurotoxic action of aluminium in experimental studies and in some clinical disorders probability connected with intoxication of aluminium.
EN
This paper presents results of investigation of stress influence on magnetic characteristics of ferrite ring cores for inductive electronics components. Ring-shaped cores were made of Ni-Zn ferrite designed for anti-lung filter cores. The results of the study indicate a significant impact of external forces stresses on the magnetic properties of ferrite cores. Such changes are very important due to their influence on the correct operation of the induction components.
EN
The results of research into the preparation of silver nanoparticles using photoreduction in the presence of hydroquinone as the reductant were discussed. Substrates for the synthesis of silver nanoparticles were ultrafine crystalline gelatine-stabilised aqueous suspensions of silver bromide. The influence of the reductant to substrate molar ratio and the medium's pH to the efficient production of silver nanoparticles were studied. The properties of resultant silver particles were examined using UV-Vis spectroscopy. Transmission electron microscopy was used for the photomicrography of silver nanoparticles suspensions.
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Synthesis of Silver Halide Nanosols

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EN
The aim of this work was to establish the average size of silver halide nanosols. The method applied was based on the optical turbidance measurements in real time of crystallization process. Dilute turbid suspensions of silver bromide, chloride and iodide stabilized by excess of halide ions and gelatin were measured over wavelength range from 450 nm to 600 nm. Experimental results were compared with the scattering theory of Rayleigh. Relation between dosing rate of reactants to dispersion system and size of obtained silver halide crystals was investigated. Interest in crystalline gelatine-stabilised aqueous suspensions of silver halide is due to their application as a substrate for the synthesis of silver nanoparticles.
EN
Movement of Dictyostelium discoideum amoebae under isotropic and anisotropic conditions was recorded and analysed with computer-aided methods and the results are presented in various manners as described in the subject literature. Cell movement under isotropic conditions showed great diversity. Some cells moved almost in a straight path whereas others in close proximity turned around with little net translocation. When cell movement under isotropic conditions was observed, no direct correlation was found between the total length of cell trajectories and the length of final displacements of the cells. It was necessary to present the results in the form of histograms, circular diagrams of cell trajectories or in scatter correlation diagrams showing the motile behaviour of many individual cells. These methods of presentation are more informative than methods which present only average values, the 'representative' behaviour of single cells, or start and end points of cell tracks. The latter methods can only illustrate but do not document the results of experiments. The use of statistical methods appears necessary in cases when it is difficult to monitor the same cells before and during experimental treatment. However, when cell movement under anisotropic conditions becomes oriented and ordered as during tactic cell movements, then the diversity in cell behaviour decreases and methods based on estimation of starting and end points of cell positions appear more credible.
EN
Paper presents utilized innovative setup for eddy current tomography and possibility of its utilization in testing oxide materials such as ferrites. Previously reported tests concerned materials with high conductivity which is the most typical usage of eddy current tests. Described tomography setup is designed for testing axisymmetric objects thus typical ferrite ring was selected for exemplary testing. Tests were conducted on ring in original state. Afterwards reference defect was created on element and measurements were repeated. Significant difference between tests results were observed, thus potential for utilization in controlling of ferrite rings manufacturing process was confirmed. Finite element method simulations were applied in order to confirm the measurement results. Calculations were conducted in open-source finite element method software, which solves the Maxwell equations in the A-V form. Modelling results confirm possibility of finite element method-based inverse tomography transformation.
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EN
Paper presents utilized innovative setup for eddy current tomography and possibility of its utilization in automotive industry. Described tomography setup is designed for testing axisymmetric objects thus motor valve was selected for exemplary testing. Tests were conducted on motor valve in original state. Afterwards reference defect was created on element and measurements were repeated. Significant difference between tests results were observed, thus potential for utilization in automotive industry was confirmed. Finite element method simulations were applied in order to confirm the measurement results. Calculations were conducted in open-source finite element method software, which solves Maxwell equations in the A-V form. Modelling results confirm possibility of finite element method-based inverse tomography transformation.
EN
Scanning electron microscopy micrograms of the elytra of Liparus glabrirostris showed a different dorsal and ventral surface and a multilayered inner structure. Hydration kinetics, sorption isotherm, and proton free induction decays are measured for hydrated elytra of the weevil species Liparus glabrirostris (Coleoptera: Curculionidae) in the atmosphere with controlled humidity. Very tightly bound water fraction with the mass Δ m/m_0 = 0.037 ± 0.004, and very short hydration time, tightly bound water Δ m/m_0 = 0.034 ± 0.009, and hydration time t_1^{h} = (3.31 ± 0.93) h, and finally loosely bound water fraction with t_2^{h} = (25.5 ± 7.8) h were distinguished. The sorption isotherm is sigmoidal in form, with the mass of water saturating primary water binding sites equal of Δ M/m_0 = 0.036. The proton free induction decays show the presence of solid signal (well fitted by a Gaussian function) from elytra (T_{2G}* ≈ 18 μs), the immobilized water fraction (T_{2L_1}* ≈ 120 μs) and mobile water pool (T_{2 L_2}* ≈ 300 μs). The hydration dependence of the water bound in elytra of L. glabrirostris, L/S is linear showing the absence of water-soluble solid fraction and negligible content of water pool "sealed" in pores of the structure.
EN
This paper presents results of tests performed on magnetostrictive delay line concerning its change in properties during temperature changes. Results indicate that an increase in temperature causes a decrease in wave amplitude and increase in the speed of propagation. The material used for the magnetostrictive delay line was an amorphous steel alloy of Fe-Si-B in tape form.
12
52%
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issue 2
397-402
EN
T*he initial stages of rehydration of salmon sperm deoxyribonucleic acid (DNA) lyophilizates were observed using hydration kinetics, sorption isotherm, and high power proton relaxometry (at 30 MHz). T*he hydration kinetics reveals (i) a very tightly bound water not removed by incubation over silica gel (A_0^{h} = 0.057 ± 0.010), (ii) a tightly bound water [saturating at A_1^{h} = 0.149 ± 0.007, hydration time t_1^{h} = (0.27 ± 0.08) h], a tightly bound water (iii) [saturating at A_2^{h} = 0.694 ± 0.039, with the hydration time t_2^{h} = (9.8 ± 3.2) h], and (iv) a loosely bound water fraction for the samples hydrated at p/p_{0} ≥ 76% [with the hydration time t_3^{h} = (44 ± 14) h, and the contribution progressively increasing with the air humidity]. For the hydration at p/p_{0} = 100%, after t_{0} = (244 ± 22) h of incubation the swelling process begins. T*he amount of additional water uptake at swelling depended on the macrostructure of the sample. Sorption isotherm is sigmoidal in form and is fitted well by the Dent model with the mass of water saturating primary binding sites Δ M/m_{0} = 0.114. Proton free induction decay is a superposition of the immobilized proton signal (Gaussian, with T*_{2S} ≈ 20 μs) and two liquid signal components coming from tightly bound (T*_{2L_1} ≈ 100 μs, with the mass saturating at Δ m/m_{0} = 0.111 ± 0.044) and loosely bound water fraction (with the amplitude proportional to the mass of water added).
EN
Tomography is a useful tool for objects reconstruction in non-destructive testing. Many kinds of tomography, depending on the penetrating wave character, are available and adapted for specific application. This paper presents new kind of tomography - conductance tomography extended with a Hall effect. Its development was motivated by the need on inhomogeneity detection in thin film Hall effect sensor, particularly graphene Hall effect sensors. Paper presents complete description of the tomographic method and tomography software developed in the GNU Octave. Inverse transformation is based on optimization method. Each shape reconstruction was done with the finite element method using the open source software: Elmer FEM and Salome. Results confirmed the suitability of the work.
EN
The paper presents results of research on the effects of mechanical stresses on the magnetostrictive properties of 13CrMo4-5 steel. Measurements of stress dependence of magnetostriction fill the gap in the state of the art enabling description of relationships between stresses applied to the samples and its magnetoelastic and magnetostrictive properties. Performed studies represent the starting point for development of unified model of both Villari (magnetoelastic) and Joule (magnetostrictive) effects under stresses in steels. The formulated model will be the basis for the development of generalized methods of interpreting the results of non-destructive testing of the state of the internal stresses in steels based on these phenomena.
EN
Nitric oxide (NO) in brain has been implicated in neuronal regulatory processes and in neuropathologies. Previously we showed that NO modified quinpirole induced yawning, a behavioral measure of dopamine (DA) D3 receptor activation in rats. The aim of this study was to characterize the effect of nitro L arginine methyl ester HCl (NAME) and L arginine HCl on reactivity of rats to the DA D1 receptor agonist SKF 38393 and DA D1 antagonist SCH 23390 in intact and neonatal6-hydroxydopamine (6 OHDA) lesioned rats (134 mug of base ICV at 3rd dayafter birth). L arginine HCl (300 mg/kg IP) increased the oral activity response in 6 OHDA lesioned rats, like SKF 38393, and induced catalepsy in intact control rats, like SCH 23390. In contrast, NAME had no effect on oral activity or catalepsy, but fully attenuated SKF 38393 induced oral activity. These findings indicate that L arginine HCl has no apparent effect at the DA D1receptor, but that NAME is effective in attenuating a DA D1 agonist - induced effect. Consequently NO may be an intracellular second mesenger for supersensitized receptors associated with DA D1 agonist induced oral activity.ity.
EN
Hydration kinetics, sorption isotherm, and proton free induction decays are measured for Ramalina terebrata thalli rehydrated from gaseous phase. Very tightly, tightly, and loosely bound water fractions are distinguished. Sorption isotherm is sigmoidal in form with the mass of water saturating primary water binding sites equal to Δ m/m_0 = 0.046. Proton free induction decays show the presence of immobilized water fraction (T_{2 L_1}* ≈ 100 μs) and mobile water pool (T_{2 L_2}* ≈ 330 μs). Sorption isotherm fitted to the NMR data shows the absence of water fraction "sealed" in pores of dry thallus.
EN
Between neighbouring bilayers of lyophilized dipalmitoylphosphatidylcholine (DPPC) multilamellar vesicles the total number of water molecules equals 9 H₂O molecules/1 DPPC molecule. One of these molecules is very tightly bound to the lipid molecule, seven are in immobilized (tightly bound) water fraction whereas the last one belongs to mobile water fraction. The rehydration from the gaseous phase of the DPPC model membranes was investigated using hydration kinetics, sorption isotherm, and high power proton relaxometry. The obtained data for DPPC were compared with these obtained for wheat photosynthetic membranes. Rehydrated photosynthetic membranes differ from DPPC model membranes in hydration kinetics. The average hydration time has a similar value: (22.0 ± 2.8) h (photosynthetic membrane) and (19.8 ± 1.6) h (DPPC), however hydration kinetics was described by one-exponential function for photosynthetic membrane, while for model membrane it shows fine double exponential form. The sigmoidal form of sorption isotherm is better fitted using Dent model than by the Brunauer-Emmett-Teller formula. The Brunauer-Emmett-Teller/Dent deviation parameter b =0.93 either for photosynthetic or for model membranes. The mass of water saturating primary water binding sites equals ΔM/m₀= 0.017 (wheat photosynthetic membranes) and 0.027 (DPPC). The detected by NMR-isotherm study mass of water "sealed" in model membrane structures was about ΔMₛ/m₀=0.182 (about 7-8 H₂O molecules/1 DPPC molecule), and ΔMₛ/m₀= 0.066 for photosynthetic membrane.
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45%
EN
The paper presents automatic and modular measurement station for the magnetic materials testing. It allows for measurements of magnetic hysteresis loops under various regimes (sine, triangle or arbitrary magnetizing field, sine or triangle magnetic flux density) and relative permeability curves. The modular nature of the system allows for measurements of magnetic parameters under additional external influences, such as temperature and stress. The system is currently used for measurements of ferrite materials parameters.
EN
The following paper presents the results of investigation on the magnetoelastic Villari effect in structural steel magnetized in the so-called Rayleigh region, which corresponds to relatively low magnetizing fields, much lower than coercive field. Two grades of structural steel were investigated during the performed measurements. Obtained results indicate significant correlation between applied mechanical stress and magnetic properties of the investigated materials.
20
39%
EN
Paper presents results of a discrete inverse tomography transformation on exemplary results from eddy current tomography setup. Eddy current phenomena is highly non-linear and measurement results are ill-posed function of distribution of physical properties of the matter (mostly electrical conductivity and magnetic permeability). Thus the inverse transformation (reconstruction of objects shape) is based on an optimization algorithm in which objects model is described as a discrete array. With the usage of Finite Element Method (FEM) tomography measurement process is reconstructed and modelling results are compared with the measurement.
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