Search results

Sort By:

Limit search:

Whole bowel irrigation (WBI) in acute iron poisoning - case report

100%

Klimaszyk D., Łukasik-Głębocka M.

Open Medicine

2006

vol. 1

issue 1

81-86

Objective: In theory, WBI (whole bowel irrigation) is indicated in iron poisoning, but the existing data are still insufficient to support or exclude its efficacy. Case report: A 46 year-old female admitted to the Toxicology Department due to suicidal ingestion of 5000 miligrams of elemental iron (57 mg/kg) in sustained-release preparation. WBI was instituted at 2 hours after ingestion, because abdominal X-ray showed mass of tablet material inside stomach and past pylorus. After 3-hour WBI subsequent X-ray revealed residual opacities in small intestine. Levels of serum iron were increasing 289 μg/dL on admission, (1,5 h post ingestion) 408 μg/dL (6 h after ingestion), 424 μg/dL (after 12 h). WBI was continued within 7 hours, until there was no radiographic evidence of toxin remaining in the gastrointestinal tract and clear rectal effluent was apparent. Subsequent serial serum iron concentrations were as follows: 389 μg/dL (after 14 h), 239 μg/dL (after 21 h), 119 μg/dL (after 36 h). Since the patient was asymptomatic did not undergo deferoxamine therapy. Patient recovered without sequelae. Conclusion: WBI seems to be beneficial in early stage of iron intoxication ensuring rapid and effective cleansing of gut, and decreasing toxin absorption. Authors believe that the use of early WBI allows to provide supportive care and avoid deferoxamine treatment.

Unusual case of double acute intoxication with tamoxifen complicated by miscarriage

71%

Sein Anand J., Chodorowski Z., Korolkiewicz R., Klimaszyk D., Łukasik-Głębocka M.

Background: A 24-year-old female had attempted suicide twice, at the age of 20 and 24, using tamoxifen. Case report: Subsequent to the first acute intoxication a development of bilateral ovarian cysts was observed. Cysts regressed spontaneously within 8 weeks. Five weeks after the second suicidal attempt, pregnant patient (15 weeks of gestation) was admitted to the hospital with vaginal bleeding and suspicion of miscarriage. The autopsy of the fetus did not reveal any gross abnormalities, whereas the microscopic examination demonstrated numerous foci of necrosis in the placental decidua. Other fetal membranes as well as the umbilical cord were normal. Conclusions:1.Acute intoxication with tamoxifen may be connected with the formation of follicular ovarian cysts.2.During pregnancy, intoxication with tamoxifen, may result in delayed miscarriage.

Refine search results

2 Open Medicine

2 2006

2 Klimaszyk D.

2 Łukasik-Głębocka M.

1 Chodorowski Z.

1 Korolkiewicz R.

1 Sein Anand J.

Search results

Whole bowel irrigation (WBI) in acute iron poisoning - case report

Unusual case of double acute intoxication with tamoxifen complicated by miscarriage