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Magnetic Heating by Tunable Arrays of Nanoparticles in Cancer Therapy

100%
Zablotskii V., Lunov O., Gómez-Polo C.
Acta Physica Polonica A
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2009
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vol. 115
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issue 1
413-417
EN
Detailed knowledge about the temperature distribution achieved in the target area is essential for the development of magnetic hyperthermia treatments. However, the temperature inhomogeneity was found in all local hyperthermia studies. As a consequence of the impossibility of guaranteeing the temperature and thus the thermal dose distribution, hyperthermia is never applied as a single treatment modality. We suggest a model that enables the calculations and optimization of the spatial-time distribution of the temperature in the target volume (i.e. tumor) caused by magnetically heated elements: (i) arrays of clusters of iron oxides magnetite (Fe_3O_4) magnetic nanoparticles, and (ii) arrays of magnetic needles. In order to find the spatial-time temperature distribution in tumor, the bioheat transfer equation is solved for the two above-mentioned arrays of magnetically heated sources embedded in the tumor. The temporal and spatial temperature distributions were calculated with regard to the effect of blood perfusion in the tumor. It is shown that a matrix of magnetic micro-needles injected in the tumor could provide rather uniform tumor heating with the center-edge temperature difference smaller than 3°C at any times during the magnetic hyperthermia treatments. The temperature profiles can be suitably adjusted by a proper choice of the magnetic nanoparticles arrangement.
2
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Three-Dimensional Micromagnetic Simulation of Spatial Distribution of Magnetization in Thick Cobalt Layers

100%
Kisielewski M., Maziewski A., Zablotskii V.
Acta Physica Polonica A
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2015
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vol. 127
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issue 2
520-522
EN
Spatial magnetization distribution of cobalt layer is studied by means of three-dimensional micromagnetic simulations in the range of cobalt thickness d from 21 to 249 nm. In this range, a spin-reorientation phase transition occurs, while the cobalt thickness increases, from a state with in-plane magnetization, to a state with out-of-plane components of magnetization. An infinite cobalt layer is modelled by the 750 nm × 750 nm × d structure consisting of cubic cells of size of 3 nm and the periodic boundary conditions. For larger thicknesses, a labyrinth, partially closed, stripe structure has been found.
3
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Coercivity of Ultrathin Magnetic Films with Perpendicular Anisotropy

100%
Zablotskii V., Kisielewski M., Tsiganenko O., Ferre J.
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EN
The calculation of the temperature dependence of the domain wall coercivity of ultrathin magnetic films with perpendicular anisotropy is reported. In this case, the magnetization reversal is supposed to occur through domain wall motion. The proposed model takes into account thermal bending fluctuations of the domain wall, which is pinned by crystal defects such as grain boundaries. A fitting procedure, applied to recently published experimental data on the field induced domain wall velocity in Au/Co films, allows us to find out realistic values of the involved parameters.
4
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Modification of Magnetic Properties of Pt/Co/Pt Films by Ga^{+} Ion Irradiation: Focused versus Uniform Irradiation

52%
Sveklo I., Mazalski P., Jaworowicz J., Jamet J., Vernier N., Mougin A., Ferré J., Kisielewski M., Zablotskii V., Bourhis E., Gierak J., Postava K., Fassbender J., Kanak J., Maziewski A.
Acta Physica Polonica A
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2018
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vol. 133
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issue 5
1215-1226
EN
30 keV Ga^{+} irradiation-induced changes of magnetic and magneto-optical properties of sputtered Pt/Co/Pt ultrathin trilayers films have been studied as a function of the ion fluence. Out-of-plane magnetic anisotropy states with enhanced magneto-optical effects were evidenced for specific values of cobalt thickness and irradiation fluence. Results obtained after uniform or quasi-uniform focused ion beam irradiation on either out-of-plane or in-plane magnetized sputtered pristine trilayers are compared. Similar irradiation-induced magnetic changes are evidenced in quasi-uniformly focused ion beam or uniformly irradiated films, grown either by sputtering or molecular beam epitaxy. We discuss on plausible common mechanisms underlying the observed effects.
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