Full-text resources of PSJD and other databases are now available in the new Library of Science.
Visit https://bibliotekanauki.pl

Refine search results

Journals help

  1. 1 Kosmos

Years help

  1. 1 2010

Authors help

  1. 1 Chadzińska M.

  2. 1 Idzik M.

Preferences help
Polish version English version Language
enabled [disable] Abstract
Number of results

Results found: 1

Number of results on page
first rewind previous Page / 1 next fast forward last

Search results

help Sort By:

help Limit search:
first rewind previous Page / 1 next fast forward last
1
Content available remote

Bezkręgowce i kręgowce zmiennocieplne jako modele w badaniach chorób zakaźnych i reakcji immunologicznych

100%
Chadzińska M., Idzik M.
Kosmos
|
2010
|
vol. 59
|
issue 3-4
467-478
EN
Ethical issues concerning application of mammalian species in experiments lead reseachers to finding of alternative animal models such as invertebrates and ectothermic vertebrates. The most studied invertebrate models are fruit fly (Drosophila melanogaster) and nematode Caenorhabditis elegans. Studies of fruit fly helped to understand mechanisms of recognition of pathogen associated molecular patterns (PAMP) by pattern recognition receptors (PRR). Whereas C. elegans enlightened our knowledge about programmed cell death - apoptosis. Recently, zebrafish (Danio rerio) and clawed frog (Xenopus laevis) are often used to study the immune system. Small size and transparency of C.elegans and larvae of zebrafish enable real-time analysis of their immune responses. All the mentioned species are now used to study immune reactions upon bacterial, fungal and viral infections. Development of new laboratory tools, including specific monoclonal antibodies, should facilitate identification of crucial, evolutionarily conserved mediators associated with these processes.
first rewind previous Page / 1 next fast forward last
JavaScript is turned off in your web browser. Turn it on to take full advantage of this site, then refresh the page.