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Severe aortic stenosis in a patient with breast cancer

100%
Mańczak R., Wilk M., Walaszkowska-Czyż A., Florczyk M., Szmit S.
OncoReview
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2016
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vol. 6
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issue 2
A49-56
EN
We present a case of 68-year-old female with severe symptomatic aortic stenosis and locally advanced breast cancer disqualified from mastectomy due to heart failure and from aortic valve replacement due to malignant neoplasm. The patient received neoadjuvant chemotherapy without anthracyclines. The aortic valve replacement was performed and then mastectomy and lymphadenectomy were made without hemodynamic complications. Adjuvant hormonotherapy was started. During 42 months of follow-up the patient remained free of recurrent cancer disease as well as no progression of heart failure was observed.
2
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Acute coronary syndromes in oncology: conservative or invasive strategies? Case study and literature review

100%
Wilk M., Walaszkowska-Czyż A., Rak A., Piłka M., Szmit S.
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vol. 8
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issue 1
5-10
EN
We present the case of a 70-year-old male patient with metastatic and castration-resistant prostate cancer as well as advanced bladder cancer, who suffered a non-ST-elevation myocardial infarction (NSTEMI). The cause of ischemia was critical left main stem stenosis, and right coronary artery stenosis. Initially, the patient was qualified for conservative treatment, but due to the intensifying symptoms of myocardial ischemia, it was decided that a hemodynamic intervention was necessary. Two drug-eluting stents were implanted, leading to clinical improvement. Following the treatment, the patient was considered as a candidate for further anti-cancer therapy. Unfortunately, due to the bladder cancer progression, anaemia and haemorrhage, his clinical condition exacerbated, and the patient died about 1 month from the cardiac intervention. Apart from the case description, the paper includes a review of literature on the treatment of acute coronary syndromes without ST-segment elevation in cancer patients.
3
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Changes in Bar Velocity and Muscular Activity During the Bench Press in Relation to the Load Lifted

86%
Gołaś A., Maszczyk A., Wilk M., Statsny P., Petr M., Wróbel G., Król H.
Central European Journal of Sport Sciences and Medicine
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2015
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vol. 11
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issue 3
95-101
EN
The purpose of the study was to determine velocity changes in relation to the load lifted along with their muscular activity. Twenty athletes representing different sport disciplines, familiar with the flat bench press took part in the research project. The ANOVA analysis revealed a significantly higher effect on range of mean velocity (F = 128.34; η2 = 1.22 with p = 0.001) and maximal velocity (F = 7 3.31; η 2 = 0 .81 w ith p = 0 .001) t o m easured l oads ( 70÷100% 1-RM) i n a scending p hase. Tukey’s p ost-hoc t ests revealed a statistically significant difference between 70% and 100% 1-RM loads, in mean velocity with p = 0.001 and maximal velocity with p = 0.001. Similarly the results revealed a statistically significant difference between 80% and 100% 1-RM loads in mean velocity (p = 0,012) and maximal velocity (p = 0,021) during the ascending phase. Relationship between velocity and the muscles activity indicates that the anterior deltoid and latissimus dorsi muscles show synergy and a significant relationship for loads 90 and 100% 1-RM. The triceps brachii muscle shows a higher relationship with velocity of the barbell for loads 70% and 80%, then the relationship of the pectoralis major muscle with velocity only for 90% 1-RM.
4
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Endocrine Responses to Physical Training and Tribulus Terrestris Supplememtation in Middle-Age Men

73%
Wilk M., Michalczyk M., Chycki J., Czuba M., Roczniok R., Gołaś A., Zając A., Maszczyk A.
Central European Journal of Sport Sciences and Medicine
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2016
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vol. 13
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issue 1
65-71
EN
The aim of this study was to evaluate the effects of steroidal saponin supplementation on blood concentration of T, GH and IGF-1. The research involved 14 men between the age of 45 and 60 years. The duration of the experiment was 12 weeks. There were two series of laboratory tests. Independent tests were conducted at the beginning and after 12 weeks of the intervention. A two-way repeated measures ANOVA revealed a statistically significant effect of the intervention on the following variables: T-Ch (η2 = 0.542), HDL-Ch (η2 = 0.522), LDL-Ch (η2 = 0.587), T (η2 = 0.603), IGF-1 (η2 = 0.512) and GH (η2 = 0.621). Thus, FFM significantly increased while TBF and BM decreased in comparison to pre-intervention levels. The analyzed results indicate that treatment or supplementation of individual hormone deficiencies can be a successful form of counteracting the aging process. Nevertheless, the effects of TT supplementation on the concentration of T as well as GH and IGF-1, requires further studies, especially in middle-aged and older subjects, along with different exercise programs. The analyzed results indicate that treatment or supplementation of individual hormone deficiencies can be a major form of counteracting the aging process.
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