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Systematyka wirusów kręgowców - aktualne dane

100%
Działo J., Deptuła W.
Kosmos
|
2010
|
vol. 59
|
issue 3-4
435-450
EN
Viral taxonomy is continuously changing. International Committee of Taxonomy of Viruses (ICTV) takes care of this taxonomy and publishes topic data from time to time. The last part - work ICTV publication came out in 2005, but there is available viral taxonomy 2009 online. The topic taxonomy of viruses infecting vertebrates consists of 9 families classified in 4 orders. Moreover, there are 23 families of viruses infecting vertebrates, that do not belong to any order and 1 genus, that has not been classified to family yet. This study consists of short description for each family of viruses, that infect vertebrates. Additionally there are some proposals to changes, which are considered by ICTV.
2
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Alkohol a zdrowie

81%
Bąbała O., Działo J., Deptuła W.
Kosmos
|
2011
|
vol. 60
|
issue 1-2
189-195
PL
Alkohol i produkty jego metabolizmu działają szkodliwie na organizmy, a szczególnie na wątrobę, trzustkę, przewód pokarmowy, układ krwionośny i rozwijający się płód. Przewlekłe spożywanie alkoholu wpływa niekorzystnie na te układy, co manifestuje się uszkodzeniem tkanek i zaburzeniami ich funkcji. Etanol i jego metabolity, głównie aldehyd octowy powodują reakcje zapalne ze strony wątroby i prowadzą do stłuszczenia, zwłóknienia oraz marskości tego narządu. Przewlekłe spożywanie alkoholu jest przyczyną przewlekłego zapalenia trzustki, które jest ważnym czynnikiem w rozwoju raka tego narządu. Alkohol jest także przyczyną zaburzonej motoryki przewodu pokarmowego oraz nieprawidłowego wchłaniania tłuszczy. Spożywanie alkoholu podczas ciąży może powodować alkoholowy zespół płodowy (FAS) u dzieci. Alkohol ma także działanie pozytywne na układ krwionośny, ale tylko wówczas, gdy jest spożywany w umiarkowanych ilościach.
EN
Alcohol and its metabolism products are harmful for organisms and especially for liver, pancreas, digestive tract, vascular system and developing foetus. Chronic alcohol consumption leads to impairment of these systems, that can be characterized by damage of tissue and their disfunction. Ethanol and its metabolites, especially acetaldehyde primarily cause inflammatory reactions in the liver and induce fatty degeneration, fibrosis and cirrhosis of the liver. Chronic alcohol consumption is the cause of chronic pancreatitis, which is a crucial factor in the development of pancreatic cancer. Alcohol is also the cause of disturbances in motor activity of digestive tract and lipids absorption. During pregnancy, alcohol induce Fetal Alcohol Syndrome (FAS). Alcohol has also stimulating ability on cardiovascular system but only in moderate amounts.
3
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Apoptosis of peripheral blood leucocytes in rabbits infected with different strains of rabbit haemorrhagic disease virus

61%
Niedźwiedzka-Rystwej P., Hukowska-Szematowicz B., Tokarz-Deptuła B., Trzeciak-Ryczek A., Działo J., Deptuła W.
Acta Biochimica Polonica
|
2013
|
vol. 60
|
issue 1
65-69
EN
The pathogenicity of RHDV (rabbit haemorrhagic disease virus) is mainly associated with its affinity to blood vessels, with causing disseminated intravascular coagulations (DIC), and with the stimulation of the host immune system. Moreover, there are implications suggesting that apoptosis may be a pivotal process in understanding the basis of viral haemorrhagic disease in rabbits - a serious infectious disease causing mortality to wild and domestic rabbits. The aim of this study is to evaluate, by means of flow cytometry, the dynamics of apoptosis in peripheral blood granulocytes and lymphocytes in rabbits experimentally infected with seven different strains of RHDV and so-called antigenic variants of RHDV denominated as RHDVa, i.e.: Hungarian 24V/89, 1447V/96, 72V/2003; Austrian 01-04, 237/04, V-412 and French 05-01. The results showed that all of the RHDV and RHDVa strains cause an increase in the number of apoptotic cells throughout the infection, which might indicate the need for further analysis of the importance of this process.
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