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1
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On the border between biology, mathematics and computer science

100%
Formanowicz P.
BioTechnologia
|
2011
|
issue 3
2
Publication available in full text mode
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Resolving power of isothermic DNA sequencing chips

100%
Formanowicz P.
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|
issue 3
3

An overall view of the process of the regulation of human iron metabolism

64%
Formanowicz D., Formanowicz P.
Biotechnologia
|
2011
|
issue 2
193-207
EN
Iron is a key component of many reactions in the human body, and by virtue of its ability to accept and donate electrons, it is required for a variety of normal cellular functions and is vital for proper growth and development. However, natural iron is rather insoluble and excess of iron is harmful since it can catalyze the formation of oxygen radicals. Fortunately, there are also mechanisms for protecting human body from excess 'free' iron. This is particularly important, given the fact that humans have very limited capacity to excrete iron. Therefore, cells have developed mechanisms to improve the solubility of iron to control intracellular iron concentrations at the point of iron absorption in the small intestine and other tissues. Since the described process is highly complex, a profound understanding of all the relationships occurring among its components is possible when a systems approach is applied to its analysis.
4
Publication available in full text mode
Content available

An overall view of the process of the regulation of human iron metabolism

64%
Formanowicz D., Formanowicz P.
BioTechnologia
|
2011
|
issue 2
5
Publication available in full text mode
Content available

A greedy algorithm for the DNA sequencing by hybridization with positive and negative errors and information about repetitions

64%
Kwarciak K., Formanowicz P.
|
2011
|
issue 1
6
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Selected aspects of endothelial dysfunction and their influence on the atherosclerosis process modeled and analyzed by Petri net based approach

51%
Formanowicz D., Kozak A., Formanowicz P.
BioTechnologia
|
2011
|
issue 4
7
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Some aspects of modeling and analysis of complex biological systems using time Petri nets

51%
Olszak J., Radom M., Formanowicz P.
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2018
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issue 1
8

DNA microarray probe design

45%
Formanowicz P., Urbaniak R., Handschuh L., Formanowicz D., Figlerowicz M.
Biotechnologia
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2008
|
issue 4
54-67
EN
DNA microarrays are widely used in many areas of biological research. They are an efficient tool for gene expression analysis due to a high level of parallelism, what means that they allow for simultaneous measuring of the transcriptional activity of all genes present in the studied genome. The quality of the results obtained using microarrays depends among other factors on the proper design of probes. Two general features which should characterize each probe are sensitivity and specificity. Since designing a set of probes having both of these properties is usually a complex task, many algorithms supporting this process have been developed and implemented. However, the designing method should be carefully chosen such that the results will match the requirements following from the nature of the biological problem to be solved. In this paper the criteria used for DNA microarray design are described and some computer based approaches are presented.
9
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Computational methods in diagnostics of chronic hepatitis C

33%
Kędziora P., Figlerowicz M., Formanowicz P., Alejska M., Jackowiak P., Malinowska N., Frątczak A., Błażewicz J.
|
2005
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vol. 53
|
issue 3
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