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Haematological changes in buprenorphine-treated mice

100%

Banerjee D., Sarkar N. K.

Folia Biologica

1997

vol. 45

157-162

Studies were carried out in adult male Swiss mice to determine whether different haematological parameters like total counts of red and white blood cells, differential counts of white blood cells, haematocrit value and blood haemoglobin level were affected by the synthetic opioid analgesic, buprenorphine, which has currently been known to be abused in several countries by the heroin addicts as a cheap substitute for heroin. The mice were daily given an intraperitoneal injection of buprenorphine (300 mug/kg) for 60 consecutive days. A severe leucopenia accompanied by decreases in lymphocyte and monocyte counts, an increase in neutrophil count, a decrease in haematocrit value, a rossette-like adherence of red blood cells to a few neutrophils and platelet satellitism were observed at the advanced stages of treatment. The abnormalities, however, reverted to normal within 45 days following withdrawal of the drug. The necessity of periodic monitoring of the blood picture in human abusers of the drug is suggested.

Anion Removal Potential of Complex Metal Oxides Estimated from Their Atomic Scale Structural Properties

52%

Chubar N., Gerda V., Mičušík M., Omastova M., Heister K., Man P., Yablokova G., Banerjee D., Fraissard J.

Acta Physica Polonica A

2018

vol. 133

issue 4

1091-1096

The main common idea of two conference papers delivered at OMEE-2017 was to demonstrate an importance of the speciation level knowledge in modern adsorption materials science. In order to prove this, two groups of adsorptive materials were used: three samples of Mg-Al-CO₃ layered double hydroxides produced by different synthesis methods and ten samples of Fe-Ce oxide-based composites with various ratios of Fe-to-Ce. In both cases of studies, it was not possible to find direct correlation between adsorptive performances of the materials and their structural properties obtained by conventional characterisation techniques. However, anion adsorptive removals of each group of inorganic composites correlated with their structural properties studied on the level of speciation. It was shown that strong anion removal potential of Mg-Al-CO₃ layered double hydroxides was associated with richness in speciation of chemical elements (Mg, Al) and interlayer anions (CO₃²¯) as well as with generous hydration. Adsorptive performances of inorganic anion exchangers based on Fe-Ce hydrous oxides were explained by simulation extended X-ray absorption fine structures simulation. The best anion removers were found to be those Fe/Ce oxide-based composites whose Fe outer shells were formed from backscattering oscillations from both O and Fe atoms.

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1 Acta Physica Polonica A

1 Folia Biologica

1 2018

1 1997

2 Banerjee D.

1 Chubar N.

1 Fraissard J.

1 Gerda V.

1 Heister K.

1 Man P.

1 Mičušík M.

1 Omastova M.

1 Sarkar N. K.

1 Yablokova G.

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Haematological changes in buprenorphine-treated mice

Anion Removal Potential of Complex Metal Oxides Estimated from Their Atomic Scale Structural Properties