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EN
The paper gives a review about kynurenic pathway metabolism of tryptophan. The implication of its metabolites in pathomechanism of several dysfunctions of tissues and organs as well as possibilities of therapeutic interference are described.
EN
The magnetic properties of both the praseodymium-aluminium perovskite PrAlO_3 crystal and its microstructured version in the form of a PrAlO_3-PrAl_{11}O_{18} eutectic have been investigated. It is shown that R\overline{3}c → Imma 205 K first-order and Imma → C 2/m near 150 K second-order phase transitions in a PrAlO_3 single crystal are suppressed after structuring the material and embedding it in a PrAl_{11}O_{18} matrix. This behavior is related to the PrAl_{11}O_{18} matrix, which mechanically hinders expansion of the microrods and in this way suppresses the phase transitions.
EN
A domain structure and crystallographic defects in Czochralski grown single crystals of Pr_xLa_{1-x}AlO_3 and Pr_xLa_{1-x-y}Mg_yAlO_3 were characterised with a number of methods including conventional and synchrotron X-ray diffraction topography, and polariscopic micrography. The observed twin domain systems were located perpendicularly to 〈100〉_{pcub} and 〈110〉_{pcub} (pseudocubic) directions. It has been confirmed that the domains are of the same orientation and a twin character as those described in literature for LaAlO_3 and LaGaO_3 crystals. The use of section transmission topography enabled to indicate that the domains are perpendicular to the (100)_{pcub} surface of the samples. The misorientation of lattice in the domains was evaluated from the white beam topographs and a tendency of its increase with increasing concentration of praseodymium was revealed.
EN
In the present paper X-ray diffraction topographic techniques were applied to a number of samples cut from Czochralski grown Pr_{x}La_{1-x}AlO_{3} crystals with different ratio of praseodymium and lanthanum. Conventional and synchrotron X-ray topographic investigations revealed differently developed domain structures dependent on the composition of mixed praseodymium lanthanum aluminium perovskites. Some large mosaic blocks were observed together with the domains. In the best crystals, X-ray topographs revealed striation fringes and individual dislocations inside large domains. Synchrotron topographs allowed us to indicate that the domains correspond to three different crystallographic planes, and to evaluate the lattice misorientation between domains in the range of 20-50 arc min.
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