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Synthesis of vinca alkaloids and related compounds 991. A new heterocyclic system

100%

Csókási P., Gács-Baitz E., Szántay C.

Utilising our earlier intermediate obtained by the umpolung reactivity of quinolizidine enamines, a new heterocyclic system: (11bSR, 15aSR)-1,2,3,6,11,14,15,15a-Octahydro-5H-indolo [2′,3′:3,4]pyrido[2,1-j]-1,6-naphthyridin-13(12H)-one was synthesised and its biological effects evaluated. Although modest, significant and selective effects were detected.

Studies on stereoselective approaches to β-carboline derivatives

76%

Milen M., Hazai L., Kolonits P., Kalaus G., Szabó L., Gömöry Á., Szántay C.

Open Chemistry

2005

vol. 3

issue 1

118-136

Transformation of β-carboline derivatives into optically active entities were studied and the de and ee values of the resulted compounds were detected.

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2 Open Chemistry

1 2005

1 2003

2 Szántay C.

1 Csókási P.

1 Gács-Baitz E.

1 Gömöry Á.

1 Hazai L.

1 Kalaus G.

1 Kolonits P.

1 Milen M.

1 Szabó L.

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Synthesis of vinca alkaloids and related compounds 991. A new heterocyclic system

Studies on stereoselective approaches to β-carboline derivatives