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Littoral cell angioma mimicking metastatic tumors

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Szumilo J., Ostrowska A., Zdunek M., Rudzki S., Chroscicki T., Czekajska-Chehab E., Burdan F.
Current Issues in Pharmacy and Medical Sciences
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2015
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vol. 28
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issue 4
247-249
EN
Littoral cell angioma is a rare primary, vascular tumor thought to originate from the endothelial cells lining the sinuses of the splenic red pulp (the “littoral cells”). It is a benign, usually asymptomatic lesion diagnosed incidentally. Ultrasound and tomography appearance is not characteristic and histopathological examination is required. This work provides a case-study of littoral cell angioma which was seen in a 55-year-old female who complained of non-specific upper abdominal pain. Computed tomography revealed multiple hypo-attenuated splenic lesions suggestive for metastasis. A splenectomy was performed and routine microscopic examination supported by immunohistochemistry reactions with CD68, CD34 and CD31 showed littoral cell angioma.
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