Familial Adenomatous Polyposis; 30-Year Observation of a Female Patient – Case Report

• Authors: Bartosz Wnęk , Marcin Strugała , Aleksandra Łożyńska-Nelke , Robert Burdyński , Piotr Krokowicz
• Languages of publication: EN

Abstracts

EN

Familial adenomatous polyposis (FAP) is a colorectal cancer syndrome caused by a germline mutation inherited in an autosomal-dominant pattern with a 100% penetrance. Our detailed case report presents a history of a 55-year-old FAP female patient who had been under constant clinical observation for 30 years. The disease was diagnosed at the age of 22. The patient underwent restorative proctocolectomy with ileal pouch-anal anastomosis (PRC-IPAA). During our follow-up extra-colonic manifestations occurred such as a desmoidtumour, fundic gland polyps in the stomach and duodenal polyps also in the periampullary region. Apart from disease-related symptoms the patient manifested other complications such as small bowel adhesive obstruction, benign breast tumours, uterine myomas, cholelithiasisand thyroid nodules. Our analysis of the above case presents advantages of a long-term medical observation of a FAP patient carried out by a specialist surgical medical centre

Keywords

EN

familial adenomatous polyposis; complications; clinical follow-up

• Publisher: De Gruyter Open
• Journal: Polish Journal of Surgery
• Year: 2015
• Volume: 87
• Issue: 2
• Pages: 86-90

Dates

published

1 - 2 - 2015

received

19 - 3 - 2014

online

3 - 7 - 2015

Contributors

author

Bartosz Wnęk

• Department of General and Colorectal Surgery, Medical University in Poznań

author

Marcin Strugała

• Department of General and Colorectal Surgery, Medical University in Poznań

author

Aleksandra Łożyńska-Nelke

• Department of General and Colorectal Surgery, Medical University in Poznań

author

Robert Burdyński

• Department of General and Colorectal Surgery, Medical University in Poznań

author

Piotr Krokowicz

• Department of General and Colorectal Surgery, Medical University in Poznań

References

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Identifiers

DOI

10.1515/pjs-2015-0024