Risk of complications and 30-day mortality after laparoscopic and open appendectomy in a Danish region, 1998-2007; a population-based study of 18,426 patients

• Authors: Sidse Bregendahl , Mette Nørgaard , Søren Laurberg , Peter Jepsen
• Languages of publication: EN

Abstracts

EN

Acute appendicitis is the most common abdominal surgical emergency, but population-based data on the risk of complications after laparoscopic appendectomy (LA) and open appendectomy (OA) are scarce.The aim of the study was to describe the risk of complications and mortality after appendectomy for acute appendicitis during a 10-year period, and to compare outcomes after LA and OA.Material and methods. Using population-based registry data, we conducted a historical cohort study in a Danish region (population 2,000,000) including all patients who underwent appendectomy for acute appendicitis during the period of 1998-2007. We used logistic regression to compare the risk of complications and 30-day mortality between LA and OA, adjusting for gender, age, severity of appendicitis, time of surgery, and calendar year. Analyses were stratified for severity of appendicitis and time period.Results. We included 18,426 patients. From 1998 to 2007 the use of LA rose from 12% to 61%, while the risk of surgically-treated complications fell from 5.7% to 3.2%, the risk of intra-abdominal infections fell from 2.4% to 1.1% and 30-day mortality fell from 0.30% to 0.23%. LA was associated with a lower risk of surgically-treated complications (adjusted odds ratio for LA vs. OA=0.70 (95% CI, 0.57-0.85), intraabdominal infections (OR=0.74 [95% CI, 0.55-0.99]) and mortality (OR=0.48 [95% CI, 0.18-1.30]). LA was safer than OA for simple and complicated appendicitis throughout the study period.Conclusions. Risk of complications and 30-day mortality decreased in Denmark between 1998 and 2007 concurrently with implementation of LA. The risk of complications was lower after LA than after OA

Keywords

EN

appendicitis; laparoscopic appendectomy; open appendectomy; complications; mortality

• Publisher: De Gruyter Open
• Journal: Polish Journal of Surgery
• Year: 2013
• Volume: 85
• Issue: 7
• Pages: 395-400

Dates

published

1 - 07 - 2013

online

13 - 08 - 2013

Contributors

author

Sidse Bregendahl

• Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark, Kierownik: prof. dr med. H. T. Sørensen
• Surgical Research Unit, Department of Surgery P, Aarhus University Hospital, Tage-Hansens Gade 2, DK-8000 Aarhus C, Denmark, Kierownik: prof. dr med. S. Laurberg

author

Mette Nørgaard

• Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark, Kierownik: prof. dr med. H. T. Sørensen

author

Søren Laurberg

• Surgical Research Unit, Department of Surgery P, Aarhus University Hospital, Aarhus, Denmark, Kierownik: prof. dr med. S. Laurberg

author

Peter Jepsen

• Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark, Kierownik: prof. dr med. H. T. Sørensen

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Identifiers

DOI

10.2478/pjs-2013-0060