Aspergillosis – Diagnostic And Therapeutic Difficulties In Critically Ill Surgical Patients

• Authors: Iwona Koper , Agnieszka Białas , Dorota Kociszewska , Nek Noori , Marek Pertkiewicz
• Languages of publication: EN

Abstracts

EN

Improving the effectiveness of the treatment of critically ill and their longer survival has increased the existence of later complications rarely seen before. Among the hospital-acquired infections such complications include infection of mold fungi. The paper presents difficulties in diagnosing and therapy of Aspergillus mold infections illustrating them with the description of cases when Aspergillus infection occurred during the treatment of critically ill, leading with treatment delay to high mortality.

Keywords

EN

aspergilosis; mold fungi; infection; treatment

• Publisher: De Gruyter Open
• Journal: Polish Journal of Surgery
• Year: 2013
• Volume: 85
• Issue: 10
• Pages: 608-614

Dates

published

1 - 10 - 2013

online

01 - 12 - 2013

Contributors

author

Iwona Koper

• Department of General Surgery and Clinical Nutrition, Warsaw Medical University, Prof. W. Orłowski CMKP Independent Public Teaching Hospital in Warsaw
• Department of Surgery, Independent Public Health Hospital in Nowe Miasto n/Pilicą

author

Agnieszka Białas

• Department of General Surgery and Clinical Nutrition, Warsaw Medical University, Prof. W. Orłowski CMKP Independent Public Teaching Hospital in Warsaw
• Department of General, Cancer, and Gastrointestinal Surgery, Prof. W. Orłowski CMKP Independent Public Teaching Hospital in Warsaw

author

Dorota Kociszewska

• Department of Clinical Bacteriology, Prof. W. Orłowski CMKP Independent Public Teaching Hospital in Warsaw

author

Nek Noori

• Department of Anaesthesiology, Independent Public Health Hospital in Rawa Mazowiecka

author

Marek Pertkiewicz

• Department of General Surgery and Clinical Nutrition, Warsaw Medical University, Prof. W. Orłowski CMKP Independent Public Teaching Hospital in Warsaw

References

• 1. Dzierżanowska D: Epidemiologia inwazyjnych zakażeń grzybiczych. Medycyna Dydaktyka Wychowanie 2008; 3: 23-32.
• 2. Kurantowska AK . Kwaśniewska J: Susceptibility to miconazole and itraconazole of Candida strains isolated from hospitalized and outpatient clinic patients. Wiad Parazyt 2009; 55(4): 415-23.
• 3. Dzierżanowska D: Prophylaxis, preemptive and empiric therapy invasive fungal infections. Zakażenia 2008; 2: 54-62.
• 4. Pasqualotto AC , Denning DW: Post-operative aspergillosis. Clin Microbial Infect 2006; 12: 1060-76.
• 5. Kałwak K, Chybicka A: What is new in the diagnostics and treatment of invasive fungal infections in hematooncological patients. Zakażenia 2010; 2: 55-63.
• 6. Kriengkauykiat J, Ito JI. Dadwal SS : Epidemiology and treatment approaches in management of invasive fungal infections. Clinical Epidemiology 2011; 3: 175-91.
• 7. Dzierżanowska D: Diagnostyka mikrobiologiczna i serologiczna układowych zakażeń grzybiczych. Zakażenia Grzybicze - wybrane zagadnienia 2006; 4: 56-69.
• 8. Jensen J, Jesus G,. Torres-Nabona M et al.: Postsurgical invasive aspergillosis: An uncommon and under-appreciated entity. Journal of Infection 2010; 60: 162-67.[Crossref][WoS]
• 9. Toka FN: NK cells are required in anti-fungal immunity. Mikrobiologia Lek 2010; 17(2): 120-23.
• 10. Staniszewska M, Jakimiak B, Rohm-RodowaldE: Antifungal agents: susceptibility of different fungal strains to various disinfecting agents. MikrobiolLek 2009; 16(4): 210-13.
• 11. Kowalczyk JR: Drug interactions of antifungals. Zakażenia 2006; 6: 62-69.
• 12. Leon C. Ruiz-Santana S. Saavedra P: A bedside scoring system (“ Candida score”) for early antifungal treatment in nonneutrpenic critically ill patients with Candida colonization. Crit Care Med 2006; 34(3): 730-736.
• 13. Kałwak K: Treatment of systemic fungal infections on the basis of proceedings from ICAA 2007. Zakażenia 2008; 1: 44-47.
• 14. Mital A, Hellmann A: Salvage therapy in invasive fungal infection. Zakażenia 2008; 1: 48-50.
• 15. Kozielec Z, Czeremszyńska-Respekta B, NawrockiS et al.: Histoclinical parameters of invasive aspergillosis in radiochemiotherapy treatedpatient. Pol Ann Med 2008;15(1): 25-33.
• 16. Lichtenstern C, Schmidt J, Knaebel HP et al.: Postoperative bacterial/fungal infections: a challenging problem in critically ill patients after abdominal surgery. Dig Surg 2007 24: 1-11.
• 17. Budak A: Review of infections caused by aspergillus fungi - progress in diagnostics and therapy. Zakażenia 2005; 4: 49-52.
• 18. Kurnatowski P, Miśkiewicz S: Invasive aspergillosis among patients undergoing a transplantation. Mikrobiol Lek 2009; 16(1): 50-53.
• 19. Pacho RA , Michalak M, Grabowska L i wsp: Zmiany w badaniach obrazowych u chorych z zakażeniami grzybiczymi. Ogólnopolski Przegl Med 2007; 4: 42-45.
• 20. Jawetz E, Mielnicki JL, Adelberg EA : Grzybica kropidlakowa. Przegl Mikrobiol Lek 1997; 484-85.
• 21. Macura AB , Skóra M, Witalis J: Fungi isolated from clinical materials and their antifungal drug susceptibility. Zakażenia 2010; 2: 60-63.

Identifiers

DOI

10.2478/pjs-2013-0091