Herpes simplex and Ebstein Barr virus encephalitis complicated with Klüver-Bucy syndrome

• Authors: Vesna Stojanović , Duško Kozić , Tatjana Mudrinić , Aleksandra Doronjski , Slobodan Spasojević , Vesna Njagulj
• Languages of publication: EN

Abstracts

EN

A case of sixteen-year-old boy with initial herpes simplex virus (HSV) and Epstein-Barr virus (EBV) encephalitis is reported. Herpesviruses are often found in cerebrospinal fluid (CSF) along with EBV. After eradication of HSV in CSF in this case, a positive polymerase chain reaction (PCR) to EBV in CSF remained along with a severe clinical picture (segmental myoclonus and Klüver-Bucy syndrome) and worsening of brain magnetic resonance imaging (MRI) findings. Neurological and psychological improvement occurred after treatment with intravenous immunoglobulin.

Keywords

EN

Herpes simplex; Ebstein Barr virus; Rncephalitis; Klüver-Bucy syndrome

• Publisher: De Gruyter Open
• Journal: Open Medicine
• Year: 2013
• Volume: 8
• Issue: 2
• Pages: 213-216

Dates

published

1 - 4 - 2013

online

23 - 1 - 2013

Contributors

author

Vesna Stojanović

• Institute for Child and Youth Health Care of Vojvodina, University of Novi Sad, School of Medicine, Hajduk Veljkova 10, 21000, Novi Sad, Serbia

author

Duško Kozić

• Institute of Oncology, Diagnostic Imaging Center, University of Novi Sad, School of Medicine, Institutski put 4, 21204, Sremska Kamenica, Serbia

author

Tatjana Mudrinić

• Institute for Child and Youth Health Care of Vojvodina, University of Novi Sad, School of Medicine, Hajduk Veljkova 10, 21000, Novi Sad, Serbia

author

Aleksandra Doronjski

• Institute for Child and Youth Health Care of Vojvodina, University of Novi Sad, School of Medicine, Hajduk Veljkova 10, 21000, Novi Sad, Serbia

author

Slobodan Spasojević

• Institute for Child and Youth Health Care of Vojvodina, University of Novi Sad, School of Medicine, Hajduk Veljkova 10, 21000, Novi Sad, Serbia

author

Vesna Njagulj

• Department of Radiology, Clinical Center of Vojvodina, University of Novi Sad, School of Medicine, Hajduk Veljkova 1, 21000, Novi Sad, Serbia

References

• [1] Whitley JR. Herpes simplex encephalitis: adolescents and adults. Antiviral 2006;71:141–148 http://dx.doi.org/10.1016/j.antiviral.2006.04.002[Crossref]
• [2] Chadaide Z, Voros E, Horvath S. Epstein-Barr virus encephalitis mimicking clinical and electroencephalographic characteristics of Herpes simplex encephalitis. J Med Virology 2008;80:1930–1932 http://dx.doi.org/10.1002/jmv.21327[WoS][Crossref]
• [3] Jha S, Patel R. Kluver-Bucy syndrome-An experience with six cases. Neurol India 2004;52:369–371
• [4] Burns A, Jacoby R, Levy R. Psychiatric phenomena in Alzheimer ’s disease. IV: Disorders of behaviour. British J Psychiatry 1990; 157: 86–94 http://dx.doi.org/10.1192/bjp.157.1.86[Crossref]
• [5] Brohi H, Wasay M, Syed NA. et al. Atypical presentation of herpes simplex encephalitis diagnosed by polymerase chain reaction (PCR). Infect Dis J Pak 2001;10:2–4
• [6] Misra UK, Kalita J, Phadke RV et al. Usefulness of various MR sequences in the diagnosis of viral encephalitis. Acta Trop 2010;116(3):206–211 http://dx.doi.org/10.1016/j.actatropica.2010.08.007[WoS][Crossref]

Identifiers

DOI

10.2478/s11536-012-0116-7