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Number of results

Journal

2008 | 6 | 4 | 562-568

Article title

Synthesis, characterization and antifungal testing of 3,4-dihydropyrimidin-2(1H)-(thio)ones containing boronic acids and boronate esters

Content

Title variants

Languages of publication

EN

Abstracts

EN
The addition of formylphenylboronic acid derivatives to thiourea and ethyl acetoacetate proceeds in the presence of an additional Lewis acid catalyst to give the corresponding 3,4-dihydropyrimidin-2(1H)-(thio)ones (Biginelli products) in moderate yield. Compounds were tested for antifungal activity against pure cultures of Aspergillus niger, Aspergillus flavus, Candida albicans and Saccharomyces cerevisiae but, unfortunately, none showed any appreciable activity. [...]

Publisher

Journal

Year

Volume

6

Issue

4

Pages

562-568

Physical description

Dates

published
1 - 12 - 2008
online
28 - 10 - 2008

Contributors

  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
author
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
author
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada
  • Department of Biology, Mount Allison University, Sackville, NB, E4L 1G7, Canada
  • Department of Chemistry, University of New Brunswick, Fredericton, NB, E3B 5A3, Canada
  • Department of Chemistry, Mount Allison University, Sackville, NB, E4L 1G8, Canada

References

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Document Type

Publication order reference

Identifiers

YADDA identifier

bwmeta1.element.-psjd-doi-10_2478_s11532-008-0064-x
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