Effective treatment of severe hypertensive crisis in 2-year-old child with neuroblastoma

• Authors: Anna Raciborska , Katarzyna Bilska , Jolanta Antoniewicz , Magdalena Rychłowska-Pruszyńska , Carlos Rodriguez-Galindo , Anna Fijałkowska
• Languages of publication: EN

Abstracts

EN

We describe a case of a 2-year-old boy with neuroblastoma and high catecholamine levels which developed a severe hypertensive crisis. An oral propranolol and oral angiotensin-converting enzyme inhibitor were used with a mild short transient benefit. However, an intravenous labetalol and oral doxazosin used for over 3 weeks resulted in successful blood pressure control. This report highlights the prolonged use of α and β-adrenergic antagonist therapy in children with neuroblastoma with refractory catecholamine-induced hypertension.

Keywords

EN

children; doxazosin; hypertensive crisis treatment; labetalol; neuroblastoma

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Education
• Journal: OncoReview
• Year: 2015
• Volume: 5
• Issue: 2
• Pages: A53-56

Contributors

author

Anna Raciborska

• Department of Surgical Oncology for Children and Y outh, Institute of Mother and Child, Warsaw, Poland

author

Katarzyna Bilska

• Department of Surgical Oncology for Children and Y outh, Institute of Mother and Child, Warsaw, Poland

author

Jolanta Antoniewicz

• Department of Nephrology, Kidney Transplantation and Hypertension, The Children’s Memorial Health Institute, Warsaw, Poland

author

Magdalena Rychłowska-Pruszyńska

• Department of Surgical Oncology for Children and Y outh, Institute of Mother and Child, Warsaw, Poland

author

Carlos Rodriguez-Galindo

• Pediatric Oncology, Dana-Farber/Boston Children’s Cancer and Blood Disorders Center , Harvard Medical School, Boston , USA

author

Anna Fijałkowska

• Department of Cardiology, Institute of Mother and Child, Warsaw, Poland

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• Document Type: article