Nutraceuticals: role in metabolic disease, prevention and treatment

• Authors: Babatunde Oluwafemi Adetuyi , Grace Onuwabhagbe Odine , Peace Abiodun Olajide , Oluwatosin Adefunke Adetuyi , Olusegun Oladimeji Atanda , Julius Kola Oloke
• Languages of publication: EN

Abstracts

EN

Nutraceuticals are products that are also used as medicine other than nutrition. A nutraceutical product may be defined as a substance, which have physiological benefits nor gives protection against chronic diseases. Nutraceuticals may also be used to improve health, delay the aging process, prevent chronic disease, increase life expectancy, or support the structure or function of the body. Nowadays, nutraceuticals has gained considerable interest due to potential nutritional safety and therapeutic effects. Recent studies have shown promising results for those compounds in various complications. Emphasis has been made to present herbal nutraceuticals effective on hard curative disorders related to oxidative stress including allergy, Alzheimer, cardiovascular, cancer, diabetes, and Parkinson’s diseases as well as obesity.

Keywords

EN

Antioxidant; Dietary fiber; Metabolic diseases; Nutraceuticals; Prebiotics; Probiotics; Vitamins

Discipline

• BIOCHEMISTRY: BIOCHEMISTRY

• Publisher: Scientific Publishing House „DARWIN”
• Journal: World News of Natural Sciences
• Year: 2022
• Volume: 42
• Pages: 1-27

Contributors

author

Babatunde Oluwafemi Adetuyi

• Department of Natural Sciences, Precious Cornerstone University, Ibadan, Nigeria

author

Grace Onuwabhagbe Odine

• Department of Natural Sciences, Precious Cornerstone University, Ibadan, Nigeria

author

Peace Abiodun Olajide

• Department of Natural Sciences, Precious Cornerstone University, Ibadan, Nigeria

author

Oluwatosin Adefunke Adetuyi

• Department of Biochemistry, Osun State University, Osogbo, Nigeria

author

Olusegun Oladimeji Atanda

• Department of Natural Sciences, Precious Cornerstone University, Ibadan, Nigeria

author

Julius Kola Oloke

• Department of Natural Sciences, Precious Cornerstone University, Ibadan, Nigeria

References

• [1] Srijan G, Sagarika M, Piyasee P, Dipjyoti D, Sankalan D. Nutraceutical and Functional Foods in Disease Prevention; 2019. 403-431
• [2] Adelaja A, Govindasamy R, Hartley M, Lambert E, Robles J, Schilling B, Sullivan K. Enhancing the Market for Nutraceuticals in the Mid-Atlantic Region. Interim Report . 1997. SR-02512-97-1
• [3] Pandey M, Verma R, Saraf A. Nutraceuticals: new era of medicine and health. Asian Journal of Pharmacy and Clinical Research, 2010, 3: 11–15
• [4] Bull E. What is nutraceutical? Pharmaceutical Journal 2000, 265: 57–58
• [5] Arreola R, Quintero-Fabian, S, Lopez-Rao I. Immuno-modulation and anti-inflammatory effects of garlic compounds. Journal of Immunology Research 2015, 1-13
• [6] Ahmadi S, Bashiri R, Ghadiri-Anari A, Nadjarzadeh A. Antioxidant supplements and semen parameters: An Evidence Based Review 2016, 14(12): 729-736
• [7] Inan S. The potential role of nutraceuticals in inflammation and oxidative stress. In: Chavarri Hueda M, ed. Nutraceuticals- Past, Present and Future. IntechOpen; 2020.
• [8] Nwosu O, Ubaoji I. Nutraceutical: history, classification and market demand. In: Egbuna C, Dable Tupas G, eds. Functional Foods and Nutraceuticals. Springer International Publishing 2020, 13-22
• [9] Kalia N. Textbook of Industrial Pharmacognocy, CBS publisher and distributor, New Delhi 2005, 204–208
• [10] Leclere C, Champ M, Boillot J, Guille G, Lecannu G, Molis C, Bornet F, Krempff M, Delort-Laval, J. Role of viscous guar guam in lowering the glycemic response after a solid meal. American Journal of Nutrition; 1994, 59: 914–921
• [11] S R Glore, D Van Treeck, A W Knehans, M Guild. Soluble fiber and serum lipids: a literature review. J Am Diet Assoc 1994 Apr; 94(4): 425-36. doi: 10.1016/0002-8223(94)90099-x
• [12] Liu S, Stampfer J, and Hu, F. Whole-grain consumption and risk of coronary heart disease: results from the Nurses’ Health study. American Journal of Clinical Nutrition 1999, 70: 412–419
• [13] Steffen L, Jacobs R, Stevens, J, Shahar E, Carithers T, Folsom, R. Associations of whole-grain, refined grain, and fruit and vegetable consumption with risks of all-cause mortality and incident coronary artery disease and ischemic stroke: the Atherosclerosis Risk in C ommunities (ARIC) Study. American Journal of Clinical Nutrition; 2003, 78: 383–390
• [14] Whelton P, Hyre D, Pedersen B, Yi Y, Whelton K, He J. Effect of dietary fiber intake on blood pressure: a metaanalysis of randomized, controlled clinical trials. Journal of Hypertension 2005, 23: 475–479
• [15] Montonen J, Knekt P, Jarvinen R, Aromaa A, Reunanen A. Whole-grain and fiber intake and the incidence of type 2 diabetes American Journal of Clinical Nutrition; 2003, 77: 622–629
• [16] Lairon D, Arnault N, Bertrais S, Planells R, Clero E, Hercberg S, Boutron-Ruault C. Dietary fiber intake and risk factors for cardiovascular disease in French adults. American Journal of Clinical Nutrition; 2005, 82: 1185–1194
• [17] Brown L, Rosner B, Willet W, Sacks F. Cholesterol lowering effects of dietary fiber: a meta-analysis. American Journal of Clinical Nutrition 1999, 69: 30–42
• [18] Cummings J. The effect of dietary fiber on fecal weight and composition. In: Spiller G, editor. Dietary fiber in human nutrition 2001, 183–252
• [19] Hord G. Eukaryotic macrobiotic crosstalk: potential mechanisms for health benefits of prebiotics and probiotics. Annual Review Nutrition 2008, 28: 215–231
• [20] Food and Agricultural Org World Health Org. Health and nutritional properties of probiotics in food including powder milk with live lactic acid bacteria; 2001
• [21] Lenoir-Wijnkoop I, Sanders E, Cabana M, Caglar E, Corthier G, Rayes N, Sherman P, Timmerman M. Probiotic and prebiotic influence beyond the intestinal tract. Nutrition Review 2007, 65: 469–89
• [22] Macfarlane S, Macfarlane G, Cummings H. Review article: prebiotics in the gastrointestinal tract. Alimentary Pharmacology and Therapeutics 2006, 24: 701–714
• [23] Escott-Stump E, Mahan L. Krause’s food, nutrition and diet therapy. 10. Philadelphia: WB Saunders Company; 2000, 553-565
• [24] Leray C, Wiesel ML, Freund M, Cazenave JP, Gachet C. Long-chain n-3 fatty acids specifically affect rat coagulation factors dependent on vitamin K: relation to peroxidative stress. Arterioscler Thromb Vasc Biol. 2001 Mar; 21(3): 459-65
• [25] Buchner H, Hengstler P, Schindler C, Meier G. N-3 polyunsaturated fatty acids in coronary heart disease—a meta analysis of randomized controlled trials. American Journal of Medicine 2002, 112: 298–304
• [26] Hiroyasu I, Rexrode K, Stampfer M, Manson J, Colditz G, Speizer F, Heinekens C, Willett W. Intake of fish and omega-3 fatty acids and risk of stroke in women. Journal of American Medical Association 2001, 285: 304–312
• [27] Carlson S. Long-chain polyunsaturated fatty acids and development of human infants. Acta Paediatrica Supplement 1999, 88: 72–77
• [28] Hodge L, Salome M, Peak J, Haby M, Xuan W, Woodlock J. Consumption of oily fish and childhood asthma risk. Medical Journal of Australia 1996, 164: 137–140
• [29] Edward R, Peet M, Shay J, Horrobin D. Omega-3 polyunsaturated fatty acid levels in the diet and in red blood cell membranes of depressed patients. Journal of Affective Disorder 1998, 48: 149–155
• [30] Elliot J. Application of antioxidant vitamins in foods and beverages. Food Technology 1999, 53: 46–48
• [31] Meydani M. Effect of functional food ingredients: vitamin E modulation of cardiovascular diseases and immune status in the elderly. American Journal of Clinical Nutrition 2000. 71:1665S–1668S
• [32] Watkins T, Bierenbaurn M, Giampalala A. Tocotrienols: biological and health effects. In: Papas AM, editor. Antioxidant status, diet, nutrition and health. Boca Raton: CRC Press; 1999. 479–496
• [33] Lee J, Koo N, Min B. Reactive oxygen species, aging and antioxidative nutraceuticals. Comprehensive Reviews in Food Science and Food Safety 2004, 3: 21–33. https://doi.org/10.1111/j.1541-4337.2004.tb00058.x
• [34] Duthie G, Gardner T, Kyle J. Plant polyphenols: are they the new magic bullet? Procurement Soc 2003, 62: 599–603
• [35] Yang G, Wang Y, Kim S, Liao J, Seril N, Chen X, Smith T, Yang S. Characterization of early pulmonary hyperproliferation and tumor progression and their inhibition by black tea in by dietary polyphenolic compounds. Annual Review of Nutrition 2001, 21: 381–406
• [36] Corder R, Douthwaite J, Lees D, Khan Q, Santos C, Wood E, Carrier J. Health: endothelin-1 synthesis reduced by red wine. Nature 2001, 414: 863–864
• [37] Sato M, Maulik N, Das D. Cardioprotection with alcohol: role of both alcohol and polyphenolic antioxidants. Annals of the New York Academic of Sciences 2002, 957: 122–135
• [38] Rice-Evans A, Miller J, Paganga G. Antioxidant properties of phenolic compounds. Trends in Plant Science Review 1997, 2: 152–159
• [39] Micallef M, Lexis L, Lewandowski P. (2007). Red wine consumption increases antioxidant status and decreases oxidative stress in the circulation of both young and old humans. Nutrition Journal 2007, 26: 27–34
• [40] Lambert J, Hong J, Yang G, Liao J, Yang, S. Inhibition of carcinogenesis by polyphenols: evidence from laboratory investigations. American Journal of Clinical Nutrition 2005, 81: 284–291
• [41] Goldbohm A, Hertog L, Brants M, Poppel G, Brandt P. Consumption of black tea and cancer risk: a prospective cohort study. Journal of the National Cancer Institute 1996, 88: 93–100
• [42] Oboh G. Antioxidant properties of some commonly consumed and underutilized tropical legumes. European Food Research and Technology 2006, 224: 61–65
• [43] Kochhar P. Dietary spices in health and diseases: I. Indian Journal of Physiology and Pharmacology 2008, 52: 106–122
• [44] Steiner M, Khan H, Holbert D, Lin R. A double-blinded crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extracts and placebo administration on blood lipids. American Journal of Clinical Nutrition 2005, 64: 866–870
• [45] Ernst, E. Complementary medicine: where is the evidence? Journal of Family Practice 2003, 52: 630–634
• [46] Bannerjee S, Mukherjee K, Maulik, K. Garlic as an antioxidant: the good, the bad and the ugly. Phytotherapy Research 2003, 17: 97–106
• [47] Sahu S. Dual role of organo sulfur compounds in foods: a review. Journal of Environmental Science and Health- C Environmental Carcinogenesis Ecotoxicology Reviews 2002, 20: 61–76
• [48] Ali M, Thomson M, Afzal M. Garlic and onions:their effects on eicosanoid metabolism and its clinical relevance. Prostaglandins Leukotrienes and Essential Fatty Acids 2002, 6: 55-73
• [49] Bhowmik D, Gopinath H, Kumar P, Duraivel S, Sampath P. Nutraceutical- A Bright Scope and Opportunity of Indian Healthcare Market. International Journal of Pharmacy 2013. 1: 30-38
• [50] Adetuyi B. O, Olajide P. A, Adetuyi O. A, Oloke J. K. Preventive Phytochemicals of cancer, as speed breakers in inflammatory signaling. Research Journal of Life Sciences, Bioinformatics, Pharmaceuticals and Chemical Sciences 2022, 8(1): 31-60
• [51] Aggarwal B. Targeting inflammation-induced obesity and metabolic diseases by curcumin and other nutraceuticals. Annual Review of Nutrition 2010, 30: 173-199
• [52] Shezhard A, Khan S, Sup Lee, Y. Curcumin molecular targets in obesity and obesity-related cancers. Future Oncology 2012, 8: 179-190
• [53] Katare C, Agarwal S, Jain M, Rani S, Saxena S, Prakash B. Lagenaria siceraria: A Potential Source of Anti-Hyperlipidemic and other pharmacological agents. Current Nutrition and Food Science 2011, 7: 1-7
• [54] Katare C, Agarwal S, Sharma S. Lagenaria siceraria: A nutraceutical for good health. International Journal of Pharmaceutics 2012, 6: 253-256
• [55] Rahman H. Bottle gourd- A vegetable for good health. Natural Product 2003, 2: 249-253
• [56] Basch E, Ulbricht C, Kuo G, Szapary P, Smith M. Therapeutic applications of fenugreek. Alternative Medicine Review 2003, 8, 20-27
• [57] Baquer N, Kumar P, Taha A, Kale R, Cowsik S, McLean P. Metabolic and molecular action of Trigonella foenum-graecum (fenugreek) and trace metals in experimental diabetes tissues. Journal of Bioscience 2011, 36: 383-396
• [58] Bhandari R, Kamdod A. Emblica officicalis (Amla): A review on potential therapeutic applications. International Journal of Green Pharmacy 2010, 6: 257-269
• [59] Vijayanand S, Wesely E. Phytochemical studies of Murraya koeingi. International Journal of Pharmaceutics Science 2010, 2: 1298-1302
• [60] Yankuzo H, Ahmed U, Santosa I, Akter F, Talib A. Beneficial effect of the leaves of Murraya koenigii (Linn.) Sprung (Rutaceae) on diabetes- induced renal damage in vivo. Journal of Ethnopharmacology 2011, 135: 88-94
• [61] Champ M. Non-nutrient bioactive substances of pulses. British Journal of Nutrition 2002, 3: 307-319

• Document Type: article