Rozpoznawanie depresji u pacjentów z chorobą Parkinsona za pomocą różnorodnych narzędzi diagnostycznych

• Authors: Krzysztof Pękala , Monika Ponichtera-Kasprzykowska , Tomasz Sobów

Title variants

EN

Depression diagnosis in patients with Parkinson’s disease using various diagnostic tools

• Languages of publication: EN PL

Abstracts

EN

Parkinson’s disease is a neurodegenerative disorder. Its main symptoms are those from the scope of motor and non-motor functions. Both groups of those symptoms considerably influence the patient’s health-related quality of life. Non-motor symptoms are frequently overlooked, and, as a consequence, poorly treated. It leads to complications in therapy and a decreased level of quality of life of both patients and their caretakers. One of the co-occurring disorders is depression. Many of the symptoms overlap with those of Parkinson’s disease. This presents additional requirements for the clinician/researcher and their psychometric tools. There are many clinical scales and self-report questionnaires successfully used for screening, diagnosis, or checking the progress in the treatment of depression. These include: Center for Epidemiologic Studies Depression Scale (CES-D), Geriatric Depression Scale (GDS), Beck Depression Inventory (BDI), Inventory of Depressive Symptoms – Self-Rated (IDS-SR), Patient Health Questionnaire (PHQ), Unified Parkinson’s Disease Rating Scale (UPDRS-Part I), Hospital Anxiety and Depression Scale (HADS), Zung Self-Rating Depression Scale (SDS), Cornell Scale for the Assessment of Depression in Dementia (CSDD), Inventory of Depressive Symptoms – Clinician (IDS-C), Hamilton Depression Rating Scale (Ham-D), Montgomery–Åsberg Depression Rating Scale (MADRS). The most efficient tools in recognizing depression in Parkinson’s disease are clinical scales, especially Hamilton and Montgomery–Åsberg scales. Their usefulness and effectiveness is high for both the screening process and for measuring the severity of depressive symptoms. Beck Depression Inventory shows similar outcomes. Slightly less research in this area has been carried out on the Inventory of Depressive Symptoms – Clinician, yet this is a promising tool. Questionnaire version of this tool – Inventory of Depressive Symptoms – Self-Rated – does not live up to the expectations in the diagnosis of depression at an appropriate level in patients with Parkinson’s disease. Similar conclusions can be drawn with respect to Unified Parkinson’s Disease Rating Scale – Part I, and the Center for Epidemiologic Studies Depression Rating Scale. For screening purposes, Geriatric Depression Scale, Hospital Anxiety and Depression Scale, Patient Health Questionnaire and Zung Self-Rating Depression Scale are valid in depression in Parkinson’s disease. Cornell Scale for the Assessment of Depression in Dementia seems a promising tool for screening once it has been tested more.

PL

Choroba Parkinsona to zaburzenie neurodegeneratywne, którego głównymi objawami są te z zakresu motoryki i tzw. pozamotoryczne. Obie grupy symptomów w znaczący sposób wpływają na poczucie jakości życia chorego. Zaburzenia pozamotoryczne często bywają pomijane, niewłaściwie diagnozowane i źle leczone, co prowadzi do komplikacji w leczeniu, gorszego funkcjonowania pacjentów i ich opiekunów. Jednym ze współwystępujących zaburzeń jest depresja. Dużo jej objawów pojawia się również w chorobie Parkinsona, co stawia przed klinicystą czy badaczem i używanymi przez nich narzędziami dodatkowe wymagania. Istnieje wiele skal klinicznych i kwestionariuszy samoopisowych z powodzeniem wykorzystywanych w przesiewie, rozpoznaniu czy sprawdzaniu postępów terapii depresji. Należą do nich: Center for Epidemiologic Studies Depression Scale (CES-D), Geriatric Depression Scale (GDS), Beck Depression Inventory (BDI), Inventory of Depressive Symptoms – Self-Rated (IDS-SR), Patient Health Questionnaire (PHQ), Unified Parkinson’s Disease Rating Scale (UPDRS-Part I), Hospital Anxiety and Depression Scale (HADS), Zung Self-Rating Depression Scale (SDS), Cornell Scale for the Assessment of Depression in Dementia (CSDD), Inventory of Depressive Symptoms – Clinician (IDS-C), Hamilton Depression Rating Scale (HAM-D), Montgomery–Åsberg Depression Rating Scale (MADRS). Z rozpoznawaniem depresji towarzyszącej chorobie Parkinsona najlepiej radzą sobie skale kliniczne, szczególnie skala Hamiltona oraz Montgomery–Åsberg. Ich przydatność i skuteczność jest duża zarówno w badaniach przesiewowych czy badaniu nasilenia objawów, jak i w stawianiu diagnozy. Podobne cechy ma kwestionariusz Becka. Nieco mniej badań w tym zakresie przeprowadzono na Inventory of Depressive Symptoms – Clinician, choć jest to narzędzie obiecujące. Wersja kwestionariuszowa tego narzędzia, Inventory of Depressive Symptoms – Self-Rated, nie spełnia oczekiwań w rozpoznawaniu depresji na odpowiednim poziomie w grupie osób z chorobą Parkinsona. Podobne wnioski należy wyciągnąć odnośnie do Unified Parkinson’s Disease Rating Scale – Part I oraz Center for Epidemiologic Studies Depression Rating Scale. Do celów przesiewowych dobrze nadają się zaś Geriatric Depression Scale, Hospital Anxiety and Depression Scale, Patient Health Questionnaire i Zung Self-Rating Depression Scale. Cornell Scale for the Assessment of Depression in Dementia może być obiecującym narzędziem do celów przesiewowych po przejściu większej liczby testów.

Keywords

EN

Parkinson’s disease; choroba Parkinsona; clinical scale; depresja; depression; diagnostic criteria; kryterium diagnostyczne; kwestionariusz samoopisowy; self-report questionnaire; skala kliniczna

Discipline

• MEDICINE: MEDICINE

• Publisher: Medical Communications
• Journal: Aktualności Neurologiczne
• Year: 2015
• Volume: 15
• Issue: 4
• Pages: 210–216

Contributors

author

Krzysztof Pękala

• Zakład Psychologii Lekarskiej, Uniwersytet Medyczny w Łodzi, Polska

author

Monika Ponichtera-Kasprzykowska

• Studium Doktoranckie, Uniwersytet Medyczny w Łodzi, Polska

author

Tomasz Sobów

• Zakład Psychologii Lekarskiej, Uniwersytet Medyczny w Łodzi, Polska

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• Document Type: review