The repair of ionizing radiation-induced DNA double-strand breaks

• Authors: P. Widlak
• Languages of publication: PL

Abstracts

EN

DNA double-strand breaks (DSB) are created by ionizing radiation, an important environmental genotoxic agent. DSB are repaired by two mechanisms associated with recombination. In eukaryotic cells homologous recombination depends on genes belonging to the RAD52 epistatic group. Alternative pathway, DNA end--joining in non-homologous recombination involves DNA-dependent protein kinase (DNA-PK).

Keywords

EN

DNA DOUBLE-STRAND BREAKS

Discipline

• EXPERIMENTAL_BIOLOGY_&_MEDICINE: EXPERIMENTAL BIOLOGY & MEDICINE

• Publisher: Index Copernicus International
• Journal: Postępy Higieny i Medycyny Doświadczalnej
• Year: 2000
• Volume: 54
• Issue: 2
• Pages: 133-148

Contributors

author

P. Widlak

• Document Type: ARTICLE
• Publication order reference: P. Wid?ak, Centrum Radiologii Doswiadczalnej i Klinicznej, Centrum Onkologii ? Instytut im. M.Sklodowskiej-Curie, Wybrzeze Armii Krajowej 15, 44-100 Gliwice, Poland